Table 1 Description of model parameters and their corresponding values.
Symbol | Description51 | \(R_0<1\) | \(R_0>1\) |
|---|---|---|---|
\(\sigma\) | Rate of daily neuron production density | \(10^{-4}\) | \(5 \times 10^{-3}\) |
\(\beta\) | Rate of neuron infection | 0.4 | 0.8 |
\(\mu _1\) | Neuron apoptosis rate | \(1.9\times 10^{-4}\) | \(1.9 \times 10^{-4}\) |
\(\mu _2\) | Rate of active microglia annihilation | \(6 \times 10^{-3}\) | \(6 \times 10^{-3}\) |
\(\mu _3\) | Rate of activated T cell annihilation | 0.015 | 0.015 |
\(d_1\) | Neuron death rate from \(\alpha\)-syn aggregations | \(3.4\times 10^{-4}\) | 0.1 |
\(a_1\) | Microglia activation from extracellular \(\alpha\)-syn and neurons | \(2\times 10^{-2}\) | \(2\times 10^{-2}\) |
\(a_2\) | T cell activation from extracellular \(\alpha\)-syn, neurons | \(2\times 10^{-2}\) | \(2\times 10^{-2}\) |
e | \(\alpha\)-syn survival percentage from neuron death | 0.5 | 0.9 |
