Table 1 Baseline characteristics of patients in the probiotic groups and the placebo group.

From: Strain specific effects of probiotic supplementation on serum amino acid profiles in Alzheimer’s disease: a randomized, double blind, placebo controlled trial

  

Placebo (n = 20)

L. rhamnosus (n = 20)

B. longum

(n = 20)

F

P valuea

 

Age

63.3 ± 5.45

68.65 ± 8.62

71.60 ± 6.97

˂0.0001

1.00

Gender

Female

8 (33.3%)

8 (33.3%)

8 (33.3%)

3.12

0.29

Male

12 (33.3%)

12 (33.3%)

12 (33.3%)

Education

Illiterate

15 (31.5%)

14 (31.5%)

17 (37%)

2.32

0.31

Educated

5 (41.2%)

6 (41.2%)

3 (17.6%)

Type of Alzheimer

Mild Alzheimer

10 (30.9%)

11 (41.8%)

11 (41.8%)

4.86

0.08

Moderate Alzheimer

10 (37.1%)

9 (20.0%)

9 (20.0%)

Weight

Weight at study baseline (kg)

67.40 ± 6.11

67.80 ± 7.78

67.90 ± 6.47

0.06

0.93

Weight at end-of-trial (kg)

66.70 ± 6.43

68.05 ± 8.14

68.20 ± 7.04

BMI

BMI at study baseline (kg/m2)

23.65 ± 2.35

23.77 ± 1.98

24.07 ± 1.06

0.16

0.84

BMI at end-of-trial (kg/m2)

23.41 ± 2.42

23.94 ± 1.77

24.26 ± 1.47

bMMSE score

 

15.47 ± 3.03

15.73 ± 3.89

15.50 ± 3.22

0.05

0.94

cCFT

 

5.4 ± 2.14

5.57 ± 1.77

5.73 ± 1.63

0.24

0.78

  1. *Values are the mean ± SD and p˂ 0.05 is considered significant.
  2. a. One-way ANOVA for quantitative variables and χ2 test for qualitative variables.
  3. b. Mini Mental State Examinatio.
  4. c. The Categorical verbal fluency test (CFT).