Table 1 Baseline characteristics of patients in the probiotic groups and the placebo group.
Placebo (n = 20) | L. rhamnosus (n = 20) | B. longum (n = 20) | F | P valuea | ||
|---|---|---|---|---|---|---|
Age | 63.3 ± 5.45 | 68.65 ± 8.62 | 71.60 ± 6.97 | ˂0.0001 | 1.00 | |
Gender | Female | 8 (33.3%) | 8 (33.3%) | 8 (33.3%) | 3.12 | 0.29 |
Male | 12 (33.3%) | 12 (33.3%) | 12 (33.3%) | |||
Education | Illiterate | 15 (31.5%) | 14 (31.5%) | 17 (37%) | 2.32 | 0.31 |
Educated | 5 (41.2%) | 6 (41.2%) | 3 (17.6%) | |||
Type of Alzheimer | Mild Alzheimer | 10 (30.9%) | 11 (41.8%) | 11 (41.8%) | 4.86 | 0.08 |
Moderate Alzheimer | 10 (37.1%) | 9 (20.0%) | 9 (20.0%) | |||
Weight | Weight at study baseline (kg) | 67.40 ± 6.11 | 67.80 ± 7.78 | 67.90 ± 6.47 | 0.06 | 0.93 |
Weight at end-of-trial (kg) | 66.70 ± 6.43 | 68.05 ± 8.14 | 68.20 ± 7.04 | |||
BMI | BMI at study baseline (kg/m2) | 23.65 ± 2.35 | 23.77 ± 1.98 | 24.07 ± 1.06 | 0.16 | 0.84 |
BMI at end-of-trial (kg/m2) | 23.41 ± 2.42 | 23.94 ± 1.77 | 24.26 ± 1.47 | |||
bMMSE score | 15.47 ± 3.03 | 15.73 ± 3.89 | 15.50 ± 3.22 | 0.05 | 0.94 | |
cCFT | 5.4 ± 2.14 | 5.57 ± 1.77 | 5.73 ± 1.63 | 0.24 | 0.78 |