Table 4 Treatment effect of probiotic supplements on serum levels of amino acids.

Parameter	P-value	Placebo Vs L. rhamnosus				Placebo Vs B. longum				L. rhamnosus Vs B. longum
		Difference	95% CI		P	Difference	95% CI		P	Difference	95% CI		P
		Difference	Lower	Upper	P	Difference	Lower	Upper	P	Difference	Lower	Upper	P
Total amino acids	0.04	1454.37	-226.31	3135.07	0.08	2132.67	464.06	3801.28	0.01^*	-678.29	-678.29	1002.39	0.42
BCAA(µmol/L)	0.03	206.08	3.94	408.23	0.04^*	255.15	53.01	457.30	0.01^*	-49.07	-251.21	153.07	0.62
Aromatic amino acids (ng/ml)	0.05	303.12	-13.77	620.01	0.06	374.34	57.45	691.23	0.02^*	0.13	-0.37	0.64	0.6

1. Values are the mean ± 95% CI and p ˂ 0.05 is considered significant.
* Adjusted based on education, type of Alzheimer’s disease, Age, BMI, and food intake.

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