Table 1 General characteristics of patients.

From: The hidden costs of PEG-rhG-CSF in autologous stem cell transplantation for newly diagnosed multiple myeloma

 

PEG-rhG-CSF (n = 33)

rhG-CSF (n = 37)

p value

 Median age, years (range)

55.8 (41–69)

54.8 (36–70)

0.587

Sex, n (%)

0.224

 Male

17 (51.5%)

25 (67.6%)

 Female

16 (48.5%)

12 (32.4%)

Induction therapy protocols

BRD

BRD

DS staging, n (%)

0.357

 I

0

0

 II

3 (9.1%)

2 (5.4%)

 III

30 (90.9%)

35 (95.6%)

ISS staging, n (%)

0.637

 I

11 (33.3%)

11 (29.7%)

 II

9 (27.3%)

14 (37.8%)

 III

13 (39.4%)

12 (32.4%)

R-ISS staging, n (%)

0.424

 I

8 (24.2%)

11 (29.7%)

 II

15 (45.5%)

17 (45.9%)

 III

10 (30.3%)

9 (24.3%)

Classification of active MM (mSMART 3.0), n (%)

0.091

 High-risk

17 (51.5%)

21 (56.8%)

 Standard-risk

16 (48.5%)

16 (43.2%)

Disease status at ASCT, n (%)

1.299

 CR

23 (69.7%)

23 (62.2%)

 VGPR

8 (24.2%)

13 (35.1%)

 PR

2 (6.1%)

1 (2.7%)

  1. PEG-rhG-CSF, Polyethylene glycolized recombinant human granulocyte-stimulating factor; rhG-CSF, Recombinant human granulocyte-stimulating factor; BRD, Bortezomib, lenalidomide and dexamethasone; DS staging, Durie–Salmon staging; ISS, International staging system; R-ISS, Revised international staging system; MM, Multiple myeloma; mSMART, Mayo stratification of myeloma and risk-adapted therapy; CR, Complete remission; VGPR, Very good partial response; PR, Partial response.