Fig. 5

Schematic diagram showing the effect of adipose tissue-derived EVs from diet-induced mice on the antioxidant properties of hepatocytes induced by oxidative stress. EV-HFD loaded approximately 8-times more CAT than EV-NC. However, when hepatocytes underwent oxidative stress, such as from H2O2 or PA, both EV-NC and EV-HFD provided similar antioxidant protective effects.