Fig. 2 | Scientific Reports

Fig. 2

From: Integrative analysis of molecular mechanisms in prostate cancer via single-cell RNA sequencing and weighted gene co-expression network analysis

Fig. 2

Epithelial cell sub clustering and pseudotime analysis (A) t-SNE plot displaying the clustering results from single-cell RNA sequencing, with different colors indicating distinct cell clusters (C0-C9). (B) Comparative t-SNE plot showing the distribution of cell clusters in control and PCa (PCA) samples. (C) Bar chart illustrating the proportion of each cell cluster (C0-C9) in individual samples (N1-N2, T1-T2). (D) Scatter plot showing the relationship between gene average expression and dispersion, with a red trend line and black points for high-variability genes. (E) Pseudotime scatter plot depicting cellular developmental trajectories based on gene expression, with different colors representing various cell clusters. (F) Pseudotime scatter plot showing the same trajectory, with cells grouped by origin (control vs. PCa), and PCa-specific clusters highlighted in red. (G) Heatmap displaying gene expression patterns across different cell clusters, with color indicating expression levels, rows representing genes, and columns representing cell clusters.

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