Fig. 1

HPLC-MS was used to determine the serum samples of the GBXZD and blank groups, as well as GBXZD decoction in positive and negative ion modes. (a) HPLC-MS results of GBXZ-medicated serum, (b) Blank serum, and (c) GBXZ decoction. (d) Venn diagram of components in GBXZ medicated serum, Blank serum, and GBXZD decoction. The orange circle represents the bioactive components of GBXZD, while the purple circle represents the metabolites of GBXZD.