Fig. 5 | Scientific Reports

Fig. 5

From: Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Guben Xiezhuo decoction against renal fibrosis

Fig. 5

Immunohistochemical analysis revealed that GBXZD attenuated the expression of inflammatory factors and extracellular matrix components in UUO rats renal tissues. (a–c) Immunohistochemical results of IL-1β, IL-6, and TNF-α in rat kidneys. (g–i) Semi-quantitative analysis of IL-1β, IL-6, and TNF-α. (d–f) Immunohistochemical results of COL-1, FN, and α-SMA in rat kidneys. (j–l) Semi-quantitative analysis of COL-1, FN, and α-SMA. *p < 0.05 vs. Model group, **p < 0.001 vs. Model group, ***p < 0.001 vs. Model group, ns for p > 0.05 vs. Model group.

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