Fig. 5 | Scientific Reports

Fig. 5

From: Impaired nutrient absorption, reduced bone mass and alterations in the gut microbiome contribute to postnatal growth retardation in a mouse model of MWS

Fig. 5

Zeb2+/− mice exhibit reduced bone mass. (a) Representative three-dimensional reconstructed images of the distal femur obtained from micro-CT scans, showing samples from each group of mice. Histomorphometric analysis of bone tissue in the region of interest (ROI) of the femur from different groups of mice (n = 3). (b) Trabecular bone volume over total volume (BV/TV); (c) structure model index (SMI); (d) cortical bone mineral density (Ct.BMD); (e) trabecular number (Tb.N); (f) trabecular separation (Tb.Sp); (g) trabecular thickness (Tb.Th).

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