Table 1 Characteristics of the study population (n = 325).

From: Comparison of interferon gamma release assays and tuberculin skin test performance for diagnosing Mycobacterium tuberculosis infection in the Pakistani population

Characteristics

ATB

Patients

(n = 150)

Healthy Individuals (n = 125)

NTBOPD Patients (n = 50)

Total Participants (n = 325)

p-value*

n (%)

n (%)

n (%)

n (%)

Age (years)

18–30

64 (42.7)

77 (61.6)

13 (26.0)

154 (47.4)

< 0.001

31–50

50 (33.3)

40 (32.0)

23 (46.0)

113 (34.8)

 

> 50

36 (24.0)

8 (6.4)

14 (28.0)

58 (17.8)

 

BMI (kg/m2)

Underweight (< 18.5)

61 (40.7)

17 (13.6)

5 (10.0)

83 (25.5)

< 0.001

Normal (18.5–24.9)

83 (55.3)

82 (65.6)

45 (90.0)

210 (64.6)

 

Overweight ( 25)

6 (4.0)

26 (20.8)

0 (0.0)

32 (9.9)

 

Male Gender

83 (55.3)

72 (57.6)

24 (48.0)

179 (55.1)

0.512

Married

101 (67.3)

51 (40.8)

41 (82.0)

193 (59.4)

< 0.001

Employed

69 (46.0)

90 (72.0)

17 (34.0)

176 (54.2)

< 0.001

Smokers

31 (20.7)

22 (17.6)

8 (16.0)

61 (18.8)

0.69

BCG Vaccinated

130 (86.7)

121 (96.8)

43 (86.0)

294 (90.5)

0.009

BCG scar present

120 (80.0)

120 (96.0)

40 (80.0)

280 (86.2)

< 0.001

TB Contact, Yes

54 (36.0)

7 (5.6)

5 (10.0)

66 (20.3)

< 0.001

Details of TB contact

Household

48 (32.0)

0 (0.0)

2 (4.0)

55 (16.9)

< 0.001

Non-Household

6 (4.0)

7 (5.6)

3 (6.0)

11(3.4)

 

No known contact

96 (64.0)

118 (94.4)

45 (90.0)

259 (79.7)

 

Districts

East

65 (43.3)

60 (48.0)

18 (36.0)

143 (44.0)

< 0.001

Central

24 (16.0)

35 (28.0)

6 (12.0)

65 (20.0)

 

West

10 (6.7)

6 (4.8)

5 (10)

21 (6.6)

 

South

17 (11.3)

4 (3.2)

11 (22.0)

32 (9.8)

 

Malir

28 (18.7)

13 (10.4)

4 (8.0)

45 (13.8)

 

Korangi

6 (4.0)

7 (5.6)

6 (12.0)

19 (5.8)

 

Ethnicity

Sindhi

60 (40.0)

26 (20.8)

17 (34.0)

103 (31.7)

< 0.001

Pathan

38 (25.3)

11 (8.8)

8 (16.0)

57 (17.5)

 

Urdu Speaking

32 (21.3)

59 (47.2)

22 (44.0)

113 (34.8)

 

Punjabi

20 (13.4)

29 (23.2)

3 (6.0)

52 (16.0)

 
  1. ATB: active tuberculosis; NTBOPD: Non-TB other pulmonary diseases; TB: tuberculosis; BCG: Bacillus Calmette et Gurerin.
  2. *Significant p-value < 0.05 by chi-square or fisher exact test.