Table 6 Sensitivity and specificity of the X-DOT-TB, QFT-Plus and TST assays in studied groups.
Study Groups | Assays | Number of Subjects | Sensitivity % (95% CI) | Specificity % (95% CI) |
|---|---|---|---|---|
Active TB patients | X-DOT-TB | 137 | 79.5 (77.4–81.5) | - |
QFT-PLUS | 52 | 55.7 (52.9–58.5) | - | |
TST | 137 | 35.8 (34.4–37.1) | - | |
Non-TB Other Pulmonary Diseases Patients | X-DOT-TB | 50 | - | 80 (76.6–83.4) |
QFT-PLUS | 20 | - | 80 (74.5–85.5) | |
TST | 50 | - | 68 (64.8–71.2) | |
Healthy Individuals | X-DOT-TB | 125 | - | 87.2 (84.9–89.4) |
QFT-PLUS | 53 | - | 77.3 (74-80.6) | |
TST | 125 | - | 88 (85.6–90.3) | |
Overall Sensitivity and Specificity | X-DOT-TB | 79.5 (77.4–81.5) (n = 137) | 85.1 (83.2–87) (n = 175) | |
QFT-PLUS | 55.7 (52.9–58.5) (n = 52) | 78.1 (75.3–80.9) (n = 73) | ||
TST | 35.8 (34.4–37.1) (n = 137) | 82.2 (80.3–84.1) (n = 175) |
