Table 9 Binary logistic regression analysis of subject characteristics associated with positive X-DOT-TB results (n = 325).

From: Comparison of interferon gamma release assays and tuberculin skin test performance for diagnosing Mycobacterium tuberculosis infection in the Pakistani population

Subject Characteristics

  

Univariate Analysis

Multivariate Analysis

Total Tested n

X-DOT-TB Positive n (%)

Crude OR

95% CI

p-

value

Adjusted OR

95% CI

p-value

Age (years)

        

18–30

154

58 (42.0)

1

     

31–50

113

50 (36.2)

1.3

0.80–2.1

0.27

1.6

0.97–2.8

0.063

> 50

58

30 (21.7)

1.7

0.96–3.2

0.65

1.9

1.0-3.9

0.046*

Gender

        

Male

179

79 (57.2)

1

     

Female

146

59 (42.8)

0.85

0.55–1.3

0.50

0.77

0.45–1.3

0.330

BMI (kg/m 2)

Overweight

32

8 (5.8)

1

     

Underweight

83

45 (32.6)

3.5

1.4–8.8

0.006*

3.9

1.4–10.8

0.007*

Normal

210

85 (61.6)

2.0

0.8–4.7

0.09

2.3

0.94–5.9

0.067

Ethnicity

Sindhi

103

52 (37.7)

1

     

Pathan

57

34 (24.6)

1.4

0.7–2.7

0.2

1.7

0.85–3.4

0.132

Urdu speaking

113

31 (22.5)

0.3

0.2–0.6

0.001*

0.44

0.24–0.81

0.008*

Punjabi

33

21 (15.2)

0.6

0.3–1.3

0.2

0.79

0.38–1.6

0.536

Smoker

No

264

116 (84.1)

1

     

Yes

61

22 (15.9)

0.7

0.4–1.2

0.2

0.56

0.28–1.1

0.101

BCG Vaccinated

No

31

14 (10.1)

1

     

Yes

294

124 (89.9)

0.88

0.4–1.8

0.7

1.78

0.76–4.1

0.183

TB Contact

No

259

100 (72.5)

1

     

Yes

66

38 (27.5)

2.1

1.2–3.7

0.006*

1.8

1.0-3.3

0.041*

Co-morbidities

No

284

123 (89.1)

1

     

Yes

41

15 (10.9)

0.7

0.3–1.4

0.4

0.67

0.32–1.3

0.286

  1. *Statistically Significant, p < 0.05.
  2. OR: Odds Radio; CI: Confidence interval.
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