Fig. 6 | Scientific Reports

Fig. 6

From: Identification and analysis of the endoplasmic reticulum stress hub genes in sepsis-associated ARDS

Fig. 6

Screening of ERS hub genes in sepsis-associated ARDS. (A) LASSO coefficient profiles of the 30 candidate genes. (B) Ten-fold cross-validation for LASSO regression with the optimal lambda value (λ = 0.0134), identifying 12 characteristic genes. (C) Error rate curve with confidence intervals for the random forest model (ntree = 500). (D) Variable importance plot showing the top genes ranked by mean decrease in Gini index in the random forest model. (E–F) Results of the SVM algorithm: the x-axis represents the number of selected features, with a cross-validation precision of 0.802 and error of 0.198. (G) Venn diagram showing the intersection of hub genes identified by LASSO, RF and SVM algorithms.

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