Table 4 Vasoactive inotropic score and hemodynamic course.

From: The predictive value of the vasoactive inotropic score in the postoperative treatment of patients suffering from infective endocarditis

 

Survivors

(n = 294)

Non-survivors

(n = 40)

p-value

Postoperative VIS

24.2 (13.5–32.0)

32.0 (20.7–50.1)

< 0.001

6 h VIS

13.1 (4.2–19.7)

21.1 (14.7–32.0)

< 0.001

12 h VIS

7.2 (2.2–14.1)

21.2 (10.2–29.4)

< 0.001

24 h VIS

3.5 (0.0-8.9)

14.7 (6.9–24.7)

< 0.001

36 h VIS

2.0 (0.0-7.6)

10.3 (3.6–19.7)

< 0.001

48 h VIS

0.0 (0.0-4.2)

11.2 (2.7–14.0)

< 0.001

Vasopressor free postoperative (%)

3 (1.0)

1 (2.5)

1.000

Vasopressor free 6 h (%)

27 (9.2)

0 (0.0)

0.090

Vasopressor free 12 h (%)

47 (16.0)

0 (0.0)

0.007

Vasopressor free 24 h (%)

97 (33.0)

4 (10.0)

0.014

Vasopressor free 36 h (%)

114 (38.8)

5 (12.5)

0.015

Vasopressor free 48 h (%)

171 (58.1)

7 (17.5)

< 0.001

Postoperative cardiac output (l/min)

8.0 (6.2–10.4)

8.2 (6.1–9.8)

0.599

6 h cardiac output (l/min)

7.2 (5.9–9.2)

6.9 (6.1–9.5)

0.278

12 h cardiac output (l/min)

6.4 (5.4-8.0)

6.6 (5.3–10.2)

0.475

24 h cardiac output (l/min)

6.6 (5.7–7.9)

6.7 (4.9–8.1)

0.594

36 h cardiac output (l/min)

7.0 (6.0-8.6)

5.6 (6.5–8.3)

0.750

48 h cardiac output (l/min)

7.0 (5.6–8.2)

6.9 (6.0-8.2)

0.658

Postoperative cardiac index (l/min/m2)

4.1 (3.2–5.2)

4.3 (2.9–5.3)

0.648

6 h cardiac index (l/min/m2)

3.7 (3.1–4.9)

3.5 (3.1–5.2)

0.226

12 h cardiac index (l/min/m2)

3.3 (2.8–4.1)

3.6 (2.8–5.3)

0.254

24 h cardiac index (l/min/m2)

3.4 (2.9–4.1)

3.2 (2.6–4.8)

0.821

36 h cardiac index (l/min/m2)

3.5 (3.0-4.3)

3.2 (2.8-5.0)

0.936

48 h cardiac index (l/min/m2)

3.5 (2.9–4.1)

3.9 (2.9–4.6)

0.197

Postoperative ScvO2 (%)

72 (67–77)

73 (66–78)

0.757

6 h ScvO2 (%)

68 (63–74)

68 (64–77)

0.242

12 h ScvO2 (%)

64 (59–70)

69 (61–75)

0.092

24 h ScvO2 (%)

64 (60–69)

64 (58–72)

0.760

36 h ScvO2 (%)

65 (59–70)

64 (58–75)

0.133

48 h ScvO2 (%)

64 (59–70)

68 (60–73)

0.026

Postoperative lactate level (mmol/l)

1.9 (1.3-3.0)

3.9 (2.2–4.9)

< 0.001

6 h lactate level (mmol/l)

1.8 (1.2–3.7)

4.7 (2.6–6.2)

< 0.001

12 h lactate level (mmol/l)

1.4 (1.0-2.6)

2.7 (1.9–5.9)

< 0.001

24 h lactate level (mmol/l)

1.3 (1.1–1.9)

1.6 (1.2–2.8)

0.027

36 h lactate level (mmol/l)

0.9 (0.8–1.2)

1.3 (1.0-1.8)

< 0.001

48 h lactate level (mmol/l)

1.1 (0.9–1.5)

1.3 (1.1–2.2)

0.016

  1. Data are presented as medians (25–75th quartiles) or as absolute numbers (percentages). VIS: vasoactive inotropic score. ScvO2: central venous saturation; Marked p-values are two-sided significant at least at the 0.05 level.
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