Table 3 Comparison of the diagnostic performance between the ECMAI-ME model and endoscopists for diagnosing Gastrointestinal stromal tumors.

From: Interpretable deep learning model diagnoses gastrointestinal stromal tumors and lesion characteristics with microprobe endoscopic ultrasonography

 

Accuracy

(%, CI)

P value

Sensitivity

(%, CI)

P value

Specificity

(%, CI)

P value

PPV

(%, CI)

NPV

(%, CI)

AI model vs. Endoscopists (N = 163)

ECMAI-ME

85.28

(79.84–90.72)

/

76.92

(65.47–88.37)

/

89.19

(83.41–94.97)

/

76.92

(65.47–88.37)

89.19

(83.41–94.97)

Expert 1

77.91

(71.55–84.28)

<0.001***

90.38

(82.37–98.40)

0.092

72.07

(63.73–80.42)

<0.001***

60.26

(49.40-71.12)

94.12

(89.12–99.12)

Expert 2

76.79

(70.20-83.18)

<0.001***

84.62

(74.81–94.42)

0.388

72.97

(64.71–81.23)

<0.001***

59.46

(48.27–70.65)

91.01

(85.07–96.95)

Novice 1

64.42

(57.07–71.77)

<0.001***

82.69

(72.41–92.97)

0.629

55.86

(46.62–65.09)

<0.001***

46.74

(36.54–56.93)

87.32

(79.58–95.06)

Novice 2

70.55

(63.55–77.55)

0.038*

67.31

(54.56–80.06)

0.267

72.07

(63.73–80.42)

<0.001***

55.56

(43.29–67.83)

83.17

(75.87–90.47)

Trainee 1

61.35

(53.87–68.83)

<0.001***

76.92

(65.47–88.37)

1.000

54.05

(44.78–63.33)

<0.001***

43.96

(33.76–54.15)

83.33

(74.72–91.94)

Trainee 2

56.44

(48.83–64.05)

<0.001***

65.38

(52.45–78.32)

0.263

52.25

(42.96–61.54)

<0.001***

39.08

(28.83–49.33)

76.32

(66.76–85.87)

AI model vs. initial diagnosis in the original reports (N = 152)

ECMAI-ME

84.87

(79.17–90.57)

/

78.00

(66.52–89.48)

/

88.24

(81.98–94.49)

/

76.47

(64.83–88.11)

89.11

(83.03–95.18)

Original reports

78.95

(72.47–85.43)

<0.001***

92.00

(84.48–99.52)

0.118

72.55

(63.89–81.21)

0.002**

62.16

(51.11–73.21)

94.87

(89.98–99.77)

  1. Abbreviations: CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.
  2. Note. Data in parentheses are 95% CI.
  3. P value were obtained from comparisons of the difference between endoscopists (or initial diagnosis in the original reports) and ECMAI-ME model.
  4. ‡ Excluding 11 lesions without exact initial diagnosis of SELs type in the original reports.
  5. * Statistically significant at p < 0.05; **p < 0.01; ***p < 0.001.