Fig. 3

miRNA-centric network generated by miRNet. The figure depicts how selected nine miRNAs and their target genes and associated diseases are connected. The blue squares represent miRNAs introduced by random forest and XGBoost approaches for having special relationship with colorectal cancer with a mean score higher than 50%. Every red circle represents a disease (Supplementary file 2) and every light green circle represent a target gene (Supplementary file 3). miRNet reported 106 diseases and 815 genes associated with the selected miRNAs.