Table 6 Gene ontology reported by ToppFun for target genes of the selected mirnas.

From: Decision tree-based machine learning methods for identifying colorectal cancer-associated microRNA signatures and their regulatory networks

GO: biological process

GO: molecular function

ID

Name

ID

Name

GO:0045934

negative regulation of nucleobase-containing compound metabolic process

GO:0043565

sequence-specific DNA binding

GO:0051253

negative regulation of RNA metabolic process

GO:0003690

double-stranded DNA binding

GO:0010558

negative regulation of macromolecule biosynthetic process

GO:1,990,837

sequence-specific double-stranded DNA binding

GO:0031327

negative regulation of cellular biosynthetic process

GO:0000976

transcription cis-regulatory region binding

GO:1,902,679

negative regulation of RNA biosynthetic process

GO:0019904

protein domain specific binding

GO:0045892

negative regulation of DNA-templated transcription

GO:0001067

transcription regulatory region nucleic acid binding

GO:0060322

head development

GO:0060090

molecular adaptor activity

GO:0031647

regulation of protein stability

GO:0008134

transcription factor binding

GO:0000122

negative regulation of transcription by RNA polymerase II

GO:0000977

RNA polymerase II transcription regulatory region sequence-specific DNA binding

GO:0043066

negative regulation of apoptotic process

GO:0003700

DNA-binding transcription factor activity

GO:0051960

regulation of nervous system development

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

GO:0043069

negative regulation of programmed cell death

GO:0030674

protein-macromolecule adaptor activity

GO:0007420

brain development

GO:0044389

ubiquitin-like protein ligase binding

GO:0007417

central nervous system development

GO:0000987

cis-regulatory region sequence-specific DNA binding

GO:0050767

regulation of neurogenesis

GO:0140262

mRNA cap binding complex binding

GO:0045893

positive regulation of DNA-templated transcription

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO:1,902,680

positive regulation of RNA biosynthetic process

GO:0031625

ubiquitin protein ligase binding

GO:0043067

regulation of programmed cell death

GO:0042393

histone binding

GO:0000902

cell morphogenesis

GO:0140110

transcription regulator activity

GO:0042981

regulation of apoptotic process

GO:0001221

transcription coregulator binding

GO:0050821

protein stabilization

  

GO:0007628

adult walking behavior

  

GO:1,903,169

regulation of calcium ion transmembrane transport

  

GO:0045597

positive regulation of cell differentiation

  

GO:0043523

regulation of neuron apoptotic process

  

GO:0048666

neuron development

  

GO:0044087

regulation of cellular component biogenesis

  

GO:0045184

establishment of protein localization

  

GO:0014009

glial cell proliferation

  

GO:0015031

protein transport

  

GO:0090659

walking behavior

  

GO:0042063

gliogenesis

  

GO:0051402

neuron apoptotic process

  

GO:0003181

atrioventricular valve morphogenesis

  

GO:0006974

DNA damage response

  

GO:0010626

negative regulation of Schwann cell proliferation

  

GO:0050768

negative regulation of neurogenesis

  

GO:0048598

embryonic morphogenesis

  

GO:1,901,339

regulation of store-operated calcium channel activity

  

GO:0043524

negative regulation of neuron apoptotic process

  

GO:0097193

intrinsic apoptotic signaling pathway

  

GO:0071824

protein-DNA complex organization