Table 2 Serum indicators values and population distribution.
From: Metabolic and hepatic biomarkers associated with MASLD in the Chinese population
Groups | Average values (Mean ± SD) | 95% CI | P-Value | Normal range | Number in testing | Number of the normal range of values | Ratio (%) | |
|---|---|---|---|---|---|---|---|---|
ALT | Normal in males | 24.6 ± 19.0 | 24.4–24.9 | < 0.001 | 0–40 U/L | 26,026 | 23,401 | 89.91 |
MASLD in males | 41.5 ± 31.8 | 41.2–41.9 | 28,781 | 18,509 | 64.31 | |||
Normal in females | 17.0 ± 16.0 | 16.9–17.2 | < 0.001 | 47,629 | 46,147 | 96.89 | ||
MASLD in females | 27.1 ± 22.8 | 26.8–27.5 | 15,472 | 13,330 | 86.16 | |||
AST | Normal in males | 23.8 ± 13.0 | 23.6–24.0 | < 0.001 | 0–40 U/L | 26,092 | 25,134 | 96.33 |
MASLD in males | 28.7 ± 15.2 | 28.5–28.9 | 28,866 | 25,476 | 88.26 | |||
Normal in females | 20.9 ± 10.6 | 20.8–21.0 | < 0.001 | 47,683 | 46,782 | 98.11 | ||
MASLD in females | 25.0 ± 14.8 | 24.8–25.2 | 15,485 | 14,420 | 93.12 | |||
AST/ALT | Normal in males | 1.12 ± 0.60 | 1.12–1.13 | < 0.001 | 0.8–1.5 | 26,024 | 17,251 | 66.29 |
MASLD in males | 0.82 ± 0.68 | 0.81–0.83 | 28,781 | 12,111 | 42.08 | |||
Normal in females | 1.41 ± 0.47 | 1.40–1.41 | < 0.001 | 47,627 | 28,723 | 60.31 | ||
MASLD in females | 1.07 ± 0.35 | 1.06–1.08 | 15,471 | 10,823 | 69.96 | |||
FBG | Normal in males | 5.46 ± 1.24 | 5.43–5.49 | < 0.001 | < 6.11 mmol/L | 7421 | 6428 | 86.62 |
MASLD in males | 5.79 ± 1.65 | 5.75–5.82 | 8453 | 6585 | 77.90 | |||
Normal in females | 5.17 ± 0.74 | 5.16–5.18 | < 0.001 | 16,563 | 15,618 | 94.29 | ||
MASLD in females | 5.82 ± 1.62 | 2.78–5.87 | 4622 | 3605 | 78.00 | |||
HDL-C | Normal in males | 1.32 ± 0.30 | 1.31–1.32 | < 0.001 | 0.91–1.96 mmol/L | 25,444 | 23,333 | 91.70 |
MASLD in males | 1.15 ± 0.25 | 1.15–1.16 | 28,145 | 24,126 | 85.72 | |||
Normal in females | 1.53 ± 0.31 | 1.52–1.53 | < 0.001 | 47,121 | 42,446 | 90.08 | ||
MASLD in females | 1.32 ± 0.28 | 1.32–1.33 | 15,379 | 14,326 | 93.15 | |||
LDL-C | Normal in males | 2.97 ± 0.77 | 2.96–2.98 | < 0.001 | 0-3.12 mmol/L | 25,444 | 15,341 | 60.29 |
MASLD in males | 3.14 ± 0.81 | 3.14–3.15 | 28,145 | 14,090 | 50.06 | |||
Normal in females | 2.87 ± 0.76 | 2.86–2.87 | < 0.001 | 47,121 | 31,517 | 66.89 | ||
MASLD in females | 3.13 ± 0.82 | 3.12–3.15 | 15,379 | 7776 | 50.56 | |||
TG | Normal in males | 1.42 ± 1.02 | 1.40–1.43 | < 0.001 | 0.3–1.7 mmol/L | 25,998 | 19,854 | 76.37 |
MASLD in males | 2.43 ± 2.04 | 2.41–2.46 | 28,760 | 11,780 | 40.96 | |||
Normal in females | 1.06 ± 0.66 | 1.06–1.07 | < 0.001 | 47,520 | 42,397 | 89.22 | ||
MASLD in females | 1.86 ± 1.42 | 1.84–1.88 | 15,479 | 8931 | 57.70 | |||
TC | Normal in males | 5.16 ± 0.99 | 5.13–5.18 | < 0.001 | 3.4–5.72 mmol/L | 6078 | 4363 | 71.78 |
MASLD in males | 5.36 ± 1.05 | 5.33–5.38 | 5293 | 3459 | 65.35 | |||
Normal in females | 5.05 ± 0.99 | 5.03–5.07 | < 0.001 | 9745 | 7354 | 75.46 | ||
MASLD in females | 5.36 ± 1.06 | 5.32–5.40 | 2324 | 1502 | 64.63 | |||
DBP | Normal in males | 75.3 ± 11.5 | 75.1–75.3 | < 0.001 | < 80 mmHg | 36,577 | 24,483 | 66.94 |
MASLD in males | 80.4 ± 11.8 | 80.3–80.5 | 38,965 | 19,207 | 49.29 | |||
Normal in females | 68.7 ± 10.5 | 68.6–68.8 | < 0.001 | 66,565 | 56,488 | 84.86 | ||
MASLD in females | 76.0 ± 11.6 | 75.9–76.2 | 20,507 | 13,072 | 63.74 | |||
SBP | Normal in males | 124.0 ± 16.6 | 123.9-124.2 | < 0.001 | 90–140 mmHg | 36,577 | 15,747 | 43.05 |
MASLD in males | 129.6 ± 16.3 | 129.4-129.7 | 38,965 | 10,895 | 27.96 | |||
Normal in females | 115.1 ± 16.9 | 115.0-115.3 | < 0.001 | 66,565 | 44,395 | 66.69 | ||
MASLD in females | 129.0 ± 19.0 | 128.7-129.2 | 20,507 | 7019 | 34.23 |
