Table 2 Comparison of the diagnostic ability of ELISA and TRFIA at different cutoff values.

From: Time-resolved fluoroimmunoassay improves sensitivity in the diagnosis of primary membranous nephropathy with low phospholipase A2 receptor antibody titer

 

AUC

AUC (95% CI)

Cutoff value

Sensitivity (%)

Specificity (%)

PLA2R-IgG4-TRFIA

0.814

0.736–0.892

25.07#

83.3

76.9

100

48.4

93.3

150

39.6

100

200*

34.1

100

PLA2R-IgG-TRFIA

0.829

0.752–0.905

0.44#

83.3

82.4

7a

26.4

100

14*

14.3

100

PLA2R-IgG-ELISA

0.712

0.594–0.830

2.84#

50.0

88

14a

19.8

90

20*

0

100

  1. # adjusted cutoff value according to ROC curve analysis.
  2. * cutoff value according to manufacture.
  3. a cutoff value according to low value of borderline.
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