Table 1 Clinical characteristics of patients.
All (n = 43) | PF-ILD (n = 12) | Non PF-ILD (n = 31) | p value | |
|---|---|---|---|---|
Age, years | 66.6 ± 11.3 | 73.1 ± 11 | 63.1 ± 10.5 | 0.0173 |
Sex, female | 21 (46.5) | 5 (41.7) | 16 (51.6) | 0.736 |
Smoking history | 21(46.5) | 7(58.3) | 14(45.2) | 0.510 |
Current smoking | 5(11.6) | 1(8.3) | 4(12.9) | 1.000 |
Diagnosis of ILD | ||||
RA | 6 (14.0) | 3 (25) | 3 (9.7) | |
SSc | 7 (16.3) | 0 (0) | 7 (22.6) | |
SJS | 5 (11.6) | 2 (16.7) | 3 (9.7) | |
DM | 8 (18.6) | 2 (16.7) | 6 (19.4) | |
AAV | 4 (9.3) | 1 (8.3) | 3 (9.7) | |
IIP | 9 (20.9) | 1 (8.3) | 8 (25.8) | |
IPF | 3 (7.0) | 3 (25) | 0 (0) | |
HP | 1 (2.3) | 0 (0) | 1 (3.2) | |
Radiological pattern | ||||
NSIP | 26(60.4) | 6(50) | 20(64.5) | |
UIP | 7(16.3) | 4(33.3) | 3(9.7) | |
OP | 5(11.6) | 0(0) | 5(16.1) | |
Others | 5(11.6) | 2(16.7) | 3(9.7) | |
Lung function | ||||
FVC % predicted | 79 0.3[72.3–92.5] | 74.2 [69.6, 83.8] | 80.3 [74.9, 94.0] | 0.168 |
FEV1.0%predicted | 84.7 [73.4, 92.3] | 78.2 [69.2, 96.2] | 85.3 [77.4, 92.2] | 0.588 |
DLCO % | 59.2 [47.0, 76.4] | 59.6 [53.6, 92.5] | 58.8 [42.0, 66.5] | 0.447 |
Laboratory data | ||||
CRP mg/dL | 0.4 [0.1, 1.0] | 0.6 [0.1, 1.9] | 0.35 [0.1, 0.79] | 0.739 |
LDH U/L | 217 [182, 248] | 202 [182, 227] | 227 [183, 256] | 0.412 |
KL-6 U/mL | 915 [439, 1357] | 715 [474, 1320] | 953 [358, 1346] | 0.591 |
BALF data | ||||
Recovery rate (%) | 55 [45, 62] | 55 [50, 58.3] | 55 [40.5, 64.0] | 0.914 |
Cell count (/µL) | 131.0 [65.0, 212.0] | 135.0 [64.0, 265.5] | 123.5 [74.3, 200.0] | 1.0 |
Lymphocytes (%) | 7.0 [3.0, 26.5] | 7.0 [3.5, 12.5] | 6.5[2.8, 28.3] | 1.0 |
Neutrophils (%) | 1.0 [0.3, 4.0] | 4.0 [1.5, 11.5] | 1 [0, 2.5] | 0.0357 |
Macrophages (%) | 91.0 [60.5, 94.5] | 87.0 [52.0, 92.0] | 91.0 [60.8, 95.3] | 0.348 |
CD4/CD8 ratio | 1.3 [0.5,3.0] | 1.4[1.1, 2.9] | 1.2[0.4, 3.5] | 0.683 |
NLR | 0.12 [0, 0.4] | 0.6 [0.2, 2.3] | 0.1 [༐, 0.2] | 0.006 |
