Table 4 Lipid profiles in circulating erythrocyte membranes according to HOMA-IR levels.

From: Erythrocyte membrane lipid profile in children and adolescents with metabolic dysfunction-associated steatotic liver disease and insulin resistance: a preliminary study

Parameters (pmol/mg of hemoglobin)

HOMA < 2.5 (n = 19) (median, Q1–Q3)

HOMA > 2.5 (n = 49) (median, Q1–Q3)

p

SM total

2185.85 (2053.07–2401.17)

2169.92 (2048.86–2305.84)

NS

SM SAT

1702.34 (1571.06–1884.90)

1718.01 (1525.14–1801.19)

NS

SM MUFA

431.45 (418.80–520.46)

487.87 (434.55–517.00)

NS

SM PUFA

7.69 (6.39–9.01)

9.07 (7.95–10.03)

0.02

SM n-3 PUFA

3.78 (2.74–4.08)

3.63 (3.38–4.37)

NS

SM n-6 PUFA

4.13 (3.49–4.78)

4.95 (4.19–6.19)

0.01

SM n-6/n-3 PUFA

1.17 (1.00–1.36)

1.38 (1.07–1.69)

0.02

PC total

3889.17 (2613.65–4844.38)

3941.88 (3113.68–4667.57)

NS

PC SAT

2197.51 (1735.44–2635.13)

2200.16 (1808.32–2603.90)

NS

PC MUFA

654.79 (569.03–820.83)

671.16 (606.25–802.98)

NS

PC PUFA

1049.06 (546.27–1410.55)

1044.96 (755.07–1262.68)

NS

PC n-3 PUFA

74.23 (59.46–106.99)

75.57 (55.42–99.90)

NS

PC n-6 PUFA

967.18 (484.86–1294.09)

963.07 (699.46–1173.32)

NS

PC n-6/n-3 PUFA

12.01 (10.90–14.07)

12.19 (11.04–14.02)

NS

PI total

189.51 (167.86–252.52)

210.62 (186.13–228.39)

NS

PI SAT

142.09 (124.41–170.96)

149.15 (133.11–162.15)

NS

PI MUFA

25.71 (21.55–28.56)

23.51 (22.04–26.85)

NS

PI PUFA

36.81 (12.64–52.99)

37.97 (25.79–42.82)

NS

PI n-3 PUFA

2.91 (2.25–3.61)

2.83 (2.50–3.23)

NS

PI n-6 PUFA

34.05 (10.35–49.66)

34.88 (23.48–40.03)

NS

PI n-6/n-3 PUFA

9.79 (4.65–1353)

11.48 (7.78–13.92)

NS

PS total

1791.80 (1030.02–1930.50)

1630 (1324.39–1986.84)

NS

PS SAT

1062.91 (549.93–1195.03)

1058.96 (840.17–1212.34)

NS

PS MUFA

119.81 (94.12–138.03)

114.93 (100.31–134.49)

NS

PS PUFA

498.17 (89.40–555.83)

490.35 (329.14–591.93)

NS

PS n-3 PUFA

111.00 (40.09–142.75)

123.25 (84.98–150.13)

NS

PS n-6 PUFA

365.74 (68.63–431.21)

353.36 (232.89–452.85)

NS

PS n-6/n-3 PUFA

2.83 (2.37–3.44)

3.17 (2.50–3.61)

NS

PE total

2275.79 (997.60–2681.43)

2586.40 (2144.71–2830.99)

NS

PE SAT

905.83 (536.74–1106.35)

947.13 (822.70–1051.42)

NS

PE MUFA

601.34 (378.49–754.87)

626.58 (520.61–710.83)

NS

PE PUFA

780.90 (151.39–852.43)

904.27 (715.22–1065.67)

0.008

PE n-3 PUFA

119.94 (25.81–135.63)

160.28 (103.43–208.34)

0.006

PE n-6 PUFA

654.08 (125.58–729.15)

750.79 (611.79–852.43)

0.02

PE n-6/n-3 PUFA

4.87 (4.22–5.96)

4.75 (3.85–5.29)

NS

  1. PC, Phosphatidylcholine; PI, Phosphatidylinositol; PE, Phosphatidylethanolamine; PS, Phosphatidylserine; SM, Sphingomyelin; SAT, Saturated fatty acids; MUFA, Monounsaturated fatty acids; PUFA, Polyunsaturated fatty acids.
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