Table 5 Correlation of membrane lipid profile with clinical and laboratory data in overweight/obese patients.

From: Erythrocyte membrane lipid profile in children and adolescents with metabolic dysfunction-associated steatotic liver disease and insulin resistance: a preliminary study

 

SM PUFA (R)

SM n-6 PUFA (R)

SM n-6/n-3 PUFA (R)

PE PUFA (R)

PE n-3 PUFA (R)

PE n-6 PUFA (R)

ALT

− 0.06

− 0.14

− 0.14

− 0.06

0.02

0.08

AST

− 0.15

− 0.24

− 0.26*

− 0.06

− 0.02

− 0.08

GGT

0.06

0.03

0.05

0.23

0.29*

0.19

Total cholesterol

− 0.22

− 0.17

− 0.02

− 0.024

− 0.06

− 0.27*

HDL-cholesterol

− 0.03

− 0.01

− 0.01

0.01

− 0.02

− 0.01

LDL-cholesterol

− 0.21

− 0.14

0.05

− 0.26*

− 0.05

− 0.29, 0.02

TG

− 0.01

− 0.01

0.05

− 0.01

0.07

− 0.04

UA

0.21

0.19

0.23

0.25

0.30*

0.24

BMI SD

0.06

− 0.02

− 0.05

− 0.14

− 0.17

− 0.12

HOMA-IR

0.31*

0.31*

0.27*

0.33**

0.28*

0.31*

  1. The significant correlations are marked as: *p < 0.05; **p ≤ 0.01.
  2. MASLD, Metabolic dysfunction associated steatotic liver disease; BMI, Body mass index; SD, Standard deviation; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; GGT, Gamma-glutamyltransferase; HDL, High-density lipoprotein; LDL, Low-density lipoprotein; TG, Triglycerides; HOMA-IR, Homeostasis model assessment score; UA, Uric acid; PE, Phosphatidylethanolamine; SM, Sphingomyelin; PUFA, Polyunsaturated fatty acids.