Fig. 2 | Scientific Reports

Fig. 2

From: The IL-36γ/PEDF/PPARγ signalling pathway plays an anti-inflammatory role in Candida albicans keratitis

Fig. 2

IL36γ and PEDF alleviate the inflammatory response of hCECs infected with CA. A, B Western blotting results validate the overexpression and knockdown efficiency of IL36γ and PEDF. (n = 3). C, D Western blotting results show IL36γ, PEDF, and IL1β expression in hCECs across different groups after 6 h of CA infection treatment. (n = 3). E PCR results showing IL1 β, IL6, CXCL8, CCL20, and S100a9 expression in hCECs across different groups after 6 h of CA infection treatment. (n = 3). F PCR results showing IL1 β, IL6, IL8, CCL20, and S100a9 expression in the supernatant of hCECs across different groups after 6 h of CA infection treatment. (n = 3). Data are presented as the mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.005 and ****p < 0.001.

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