Table 2 Changes of electrocardiographic parameters after Statin therapy.
From: A randomized controlled trial of the short-term effect of rosuvastatin on the corrected QT interval
Variables | Rosuvastatin (n = 228) | Atorvastatin (n = 238) | p-Value |
|---|---|---|---|
Change of heart rate (bpm) | − 3.70 ± 9.50 | − 4.73 ± 10.32 | 0.261 |
Change of QTc (ms) | 6.57 ± 20.32 | − 0.83 ± 22.07 | < 0.001 |
Increased QTc interval | 143 (62.7%) | 111 (46.6%) | < 0.001 |
QT prolongation (baseline) | 26 (11.4%) | 38 (16.0%) | 0.153 |
QT prolongation (follow - up) | 40 (17.5%) | 33 (13.9%) | 0.275 |
Newly emerged QT prolongation | 21 (9.2%) | 10 (4.2%) | 0.030 |
Severe QT prolongation | 6 (2.6%) | 4 (1.7%) | 0.537 |