Fig. 4
From: IL6/STAT3 induced GRWD1 mediates aerobic glycolysis via P53/GLUT1 signal axis in colon carcinoma
The effect of GRWD1 on glycolysis in CRC cells. (A) The GSEA enrichment analysis of GRWD1 high expression with biological processes. GRWD1 knockdown (B) and overexpression (C) in SW480 and RKO cells. (D) The values of ECAR, glycolysis, glycolytic capacity and glycolytic reverse in GRWD1 knockdown cells were represented. (E) The relative OCR, basal respiration, ATP production, and maximum respiration were shown in GRWD1 knockdown cells. (F) The effect of GRWD1 on glucose uptake. (G) The effect of GRWD1 on lactate release.
