Fig. 1
(a) DEGs Volcano plotof dataset GSE7307. The x-axis represents log2FC, the y-axis represents -log10(pvalue), red dots represent up-regulated genes, blue dots represent down-regulated genes, and gray dots represent genes with non-significant differences. (b) DEGs heatmap of dataset GSE7307.The upper part is a density heatmap of the expression levels of the top 10 up- and down-regulated genes, showing lines for the five percentiles and the mean value; the lower part is a heatmap of the expression levels of the top 10 up- and down-regulated genes. (c) Gene intersection Venn diagram (d) GO gene enrichment map. Left half shows GO enrichment analysis. Inner circle has bars for z-scores (higher bars mean darker and more upregulated). Outer circle is a scatter plot of pathway genes, highlighting up/downregulated ones. Right half details GO-rich pathways, dividing top 5 gene-rich pathways into BP, CC, and MF. (e) The left half shows enriched gene names. Darker colors mean higher logFC values; blue indicates downregulated genes. The right half shows enriched functional pathways, colored differently. Larger color blocks mean more genes are enriched in the pathway. (f) PPI protein interaction network. PPI protein interaction network: Circles denote genes, lines indicate interactions, and color from yellow to purple shows degree size from small to large. (g)Venn diagram of central genes.
