Fig. 5 | Scientific Reports

Fig. 5

From: Comprehensive characterization of lysosome-dependent cell death reveals prognostic significance and immune landscape in colon adenocarcinoma

Fig. 5

Identification of gene subtype characteristics associated with LDCD molecular subgroups. (A) Differential expression analysis of genes among LDCD molecular subgroups with thresholds of |fold change|≥ 2 and adjusted p-value < 0.05. (B,C) GO and KEGG enrichment analyses of DEGs among LDCD molecular subgroups. (D) Identification of gene subtypes based on unsupervised consensus clustering analysis of DEGs. (E) Unsupervised PCA plot of gene subgroups. (F) Clinical prognosis curve analysis of gene subtypes. (G) Expression profiles of DEGs across different clinicopathological features and molecular subgroups. (H) Differential expression analysis of the LDCD signature within gene subgroups.

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