Table 1 Comparison of categorical variables between cases (individuals with obesity) and controls (individuals with normal BMI).
From: UCP3 gene variants and obesity in a Pakistani sample population
Parameter | Category | Cases | Controls | p-value | p-value (corrected) |
|---|---|---|---|---|---|
Sociodemographic factors | |||||
Age | Median (IQR) | 29 (17) | 27 (10) | 0.142 | 0.168 |
Mean ranks | 208.98 | 192.02 | |||
Gender | Male | 105 | 112 | 0.482 | 0.482 |
Female | 95 | 88 | |||
Marital status | Single | 103 (43.5%) | 134 (56.5%) | 0.002 | 0.003 |
Married | 97 (59.5%) | 66 (40.5%) | |||
Parental consanguinity | Yes | 47 (54.7%) | 39 (45.3%) | 0.330 | 0.358 |
No | 153 (48.7%) | 161 (51.3%) | |||
Family history of obesity | Yes | 105 (57.7%) | 77 (42.3%) | 0.006 | 0.009 |
No | 95 (44.0%) | 121 (56.0%) | |||
Obesity-related physical signs | |||||
Hyperlipidemia signs | Yes | 23 (85.2%) | 4 (14.8%) | < 0.001 | 0.0003 |
No | 177 (47.5%) | 196 (52.5%) | |||
Acanthosis nigricans | Yes | 113 (89.0%) | 14 (11.0%) | < 0.001 | < 0.001 |
No | 87 (31.9%) | 186 (68.1%) | |||
Axillary striae | Yes | 120 (87.6%) | 17 (12.4%) | < 0.001 | < 0.001 |
No | 80 (30.4%) | 183 (69.6%) | |||
Abdominal striae | Yes | 122 (87.8%) | 17 (12.2%) | < 0.001 | < 0.001 |
No | 78 (29.9%) | 183 (70.1%) | |||
Obesity-related comorbidities | |||||
Joint problems | Yes | 88 (77.2%) | 26 (22.8%) | < 0.001 | < 0.001 |
No | 112 (39.2%) | 174 (60.8%) | |||
Depression | Yes | 76 (75.2%) | 25 (24.8%) | < 0.001 | < 0.001 |
No | 124 (41.5%) | 175 (58.5%) | |||
Menstrual cycle (females only) | Regular | 60 (44.4%) | 75 (55.6%) | 0.007 | 0.009 |
Irregular | 30 (71.4%) | 12 (28.6%) | |||
Menopause | 5 (83.3%) | 1 (16.7%) | |||
Obesity-related stigma | |||||
Cases only (individuals with obesity) | Yes | 93 (46.5%) | – | ||
No | 107 (53.5%) | ||||
Males | Yes | 31 (29.5%) | < 0.001 | < 0.001 | |
No | 74 (70.5%) | ||||
Females | Yes | 62 (65.3%) | |||
No | 33 (34.7%) | ||||
