Table 6 Characteristics of cases carrying case-exclusive variants.

From: UCP3 gene variants and obesity in a Pakistani sample population

Chromosomal location

Variant ID

Number of cases

Genotype

Sex

BMI

FHO

Ethnicity

Obesity onset

73712720 (CT > C)

rs35517703

04

All heterozygous

02 males

02 females

33.7 ± 1.7

Yes (2/4 cases)

1 Urdu speaking, 1 Pakhtun,

2 Sindhis

3 in 20’s

1 in 30’s

73716530 (G > C)

rs142107918

01

Homozygous for alternate allele

Male

36.5

Yes

Punjabi

30’s

73718482 (CTTT > C)

rs928421426

02

Both heterozygous

Both females

37.9 ± 4.5

Yes (1/2 cases)

1 Chitrali,

1 Urdu speaking

1 since childhood 1 case in 20’s

  1. FHO included information about obesity in first-degree relatives (parents and full siblings). BMI is reported as mean ± standard deviation. Abbreviations: BMI, body mass index; FHO, family history of obesity.
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