Table 2 Correlation analysis between CD159A and genes markers of immune cells in TIMER2.0.

From: Identification of CD159A as a prognostic and immune biomarker in kidney renal clear cell carcinoma

Description

Gene markers

KIRC (n = 533)

None

Cor

P

 

Purity

Cor

p

 

B cell

CD79A

0.324

1.61E-14

***

0.285

4.74E-10

***

CD19

0.344

2.74E-16

***

0.313

6.58E-12

***

MS4A1

0.389

1.11E-20

***

0.362

1.11E-15

***

T cell

CD2

0.51

1.37E-36

***

0.474

3.63E-27

***

CD3D

0.495

2.28E-34

***

0.457

3.39E-25

***

CD3E

0.476

1.68E-31

***

0.435

9.33E-23

***

Monocyte

CSF1R

0.289

1.01E-11

***

0.245

1.01E-07

***

CD86

0.369

1.27E-18

***

0.33

3.43E-13

***

CD8+T cell

CD8A

0.425

8.35E-25

***

0.381

2.41E-17

***

CD8B

0.414

1.73E-23

***

0.377

4.68E-17

***

M1 Macrophage

NOS2

 – 0.03

4.83E-01

NS

 – 0.064

1.71E-01

NS

PTGS2

 – 0.012

7.74E-01

NS

 – 0.031

5.13E-01

NS

IRF5

0.181

2.75E-05

***

0.168

2.89E-04

***

M2 Macrophage

CD163

0.251

4.28E-09

***

0.223

1.34E-06

***

MS4A4A

0.332

3.57E-15

***

0.297

7.19E-11

***

VSIG4

0.296

3.23E-12

***

0.244

1.09E-07

***

Neutrophils

CEACAM8

0.039

3.65E-01

NS

0.046

3.23E-01

NS

ITGAM

0.279

5.34E-11

***

0.24

1.85E-07

***

CCR7

0.264

5.64E-10

***

0.217

2.70E-06

***

Dendritic cell

HLA-DPA1

0.388

1.52E-20

***

0.359

1.70E-15

***

HLA-DPB1

0.383

4.58E-20

***

0.361

1.28E-15

***

HLA-DQB1

0.284

2.21E-11

***

0.246

9.01E-08

***

HLA-DRA

0.399

9.57E-22

***

0.38

2.87E-17

***

NRP1

 – 0.037

3.94E-01

NS

 – 0.063

1.76E-01

NS

CD1C

0.219

3.24E-07

***

0.185

6.27E-05

***

ITGAX

0.245

1.07E-08

***

0.216

2.92E-06

***

NK

FGFBP2

0.13

2.63E-03

**

0.121

9.49E-03

**

FCGR3A

0.361

7.73E-18

***

0.318

2.81E-12

***

CX3CR1

0.139

1.26E-03

**

0.102

2.84E-02

*

GNLY

0.402

4.06E-22

***

0.358

2.33E-15

***

NKG7

0.477

1.27E-31

***

0.433

1.84E-22

***

TYROBP

0.393

3.59E-21

***

0.348

1.45E-14

***

PRF1

0.434

6.00E-26

***

0.398

5.96E-19

***

NKT

KIR2DL1

0.232

6.21E-08

***

0.222

1.48E-06

***

KIR2DL3

0.257

1.69E-09

***

0.255

2.65E-08

***

KIR2DL4

0.409

6.90E-23

***

0.377

5.40E-17

***

KIR2DS4

0.203

2.42E-06

***

0.197

2.08E-05

***

KIR3DL1

0.249

5.25E-09

***

0.252

4.12E-08

***

KIR3DL2

0.309

2.91E-13

***

0.305

2.15E-11

***

KIR3DL3

0.162

1.69E-04

***

0.149

1.30E-03

**

Tfh

BCL6

 – 0.009

8.33E-01

NS

 – 0.018

7.06E-01

NS

IL21

0.182

2.38E-05

***

0.165

3.62E-04

***

Th2

GATA3

0.188

1.28E-05

***

0.14

2.67E-03

**

STAT5A

0.281

4.11E-11

***

0.241

1.70E-07

***

STAT6

 – 0.035

4.15E-01

NS

 – 0.015

7.52E-01

NS

IL13

0.073

9.04E-02

NS

0.069

1.37E-01

NS

Th17

STAT3

 – 0.031

4.74E-01

NS

 – 0.062

1.82E-01

NS

IL17A

0.071

1.00E-01

NS

0.06

1.98E-01

NS

Th1

TBX21

0.425

9.93E-25

***

0.389

4.13E-18

***

STAT4

0.456

9.30E-29

***

0.435

9.95E-23

***

STAT1

0.295

3.78E-12

***

0.251

4.65E-08

***

IFNG

0.454

2.07E-28

***

0.413

1.96E-20

***

TNF

0.127

3.41E-03

**

0.085

6.84E-02

NS

Treg

TGFB1

0.103

1.71E-02

*

0.077

9.85E-02

NS

CCR8

0.432

1.28E-25

***

0.401

3.00E-19

***

STAT5B

 – 0.084

5.17E-02

NS

 – 0.079

9.15E-02

NS

FOXP3

0.415

1.52E-23

***

0.373

1.08E-16

***

T cell exhaustion

GZMB

0.386

2.08E-20

***

0.347

1.81E-14

***

HAVCR2

0.108

1.27E-02

*

0.065

1.64E-01

NS

LAG3

0.403

3.45E-22

***

0.365

5.89E-16

***

PDCD1

0.413

2.06E-23

***

0.375

7.94E-17

***

CTLA4

0.413

2.07E-23

***

0.374

1.04E-16

***

TAM

CD68

0.25

5.09E-09

***

0.236

3.02E-07

***

IL10

0.238

2.52E-08

***

0.18

1.03E-04

***

CCL2

 – 0.002

9.55E-01

NS

 – 0.043

3.59E-01

NS

  1. Correlation R value was calculated by Spearman’s algorithm and adjusted by tumor purity.
  2. *p < 0.05, **p < 0.01, ***p < 0.001.
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