Fig. 2 | Scientific Reports

Fig. 2

From: Prognostic and predictive implications of tumor suppressor gene alterations in non-small cell lung cancer

Fig. 2

Prognostic associations of genetic biomarkers and OS—univariate and multivariate analyses. ‡KRAS G12C vs. KRAS WT. *For the genes not baited by F1L, the analyses were conducted in the subgroup of patients profiled by F1CDx and F1LCDx (N = 134). ^The analysis was conducted in the TMB-evaluable population (N = 120). †The analysis was conducted in the PD-L1-evaluable population (N = 175). ¥Frequency of the Mut group. Violation of PH assumption for TP53, STK11, RB1, and MYC in univariate analyses, and TP53, MTAP, RB1, and MYC in multivariate analyses. aHR, adjusted HR; cHR, crude HR; CI,confidence interval; HR, hazard ratio; Mut, mutant; TMB-H, tumor mutational burden high; WT, wild-type.

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