Table 2 Concordance of ploidy and sex determination between trophectoderm biopsy and spent culture media.

From: Extended blastocyst culture improves DNA yield in non-invasive preimplantation genetic testing for aneuploidy but diagnostic specificity remains limited

 

Day 5 (%, n/N)

Day 6 (%, n/N)

Total (%, n/N)

p-value

Total concordance

76.8% (63/82)

73.4% (69/94)

75.9% (132/174)

NS

Full concordance

46.3% (38/82)

52.1% (49/94)

50.0% (87/174)

NS

Partial concordance

30.5% (25/82)

21.3% (20/94)

25.9% (45/174)

NS

Sex concordance

100% (82/82)

100% (94/94)

100% (174/174)

NS

  1. NS, not statistically significant. Full concordance refers to cases where both TE biopsy and SCM results matched completely. Partial concordance includes cases where some discrepancies were observed between TE biopsy and SCM results. Sex concordance was 100% across all samples.
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