Table 2 Association between echocardiographic variables and diastolic function score.

From: The prognostic importance of left ventricular diastolic function in primary mitral regurgitation and its relation to structural changes by CMR

Variable

DF score = 0

(n = 32)

DF score = 1

(n = 40)

DF score = 2

(n = 68)

DF score = 3

(n = 33)

P

LAVI (ml/m2)

36.5 [28.2–42.8]

48.5 [41.1–73.9]

59.9 [43.4–79.5]

52.6 [45.2–63.8]

 < 0.001

Mitral E (cm/s)

96.3 [86.4–114.5]

111.8 [86.3–143.7]

112.5* [95.3–139.2]

141.3*¶+ [116.4–162.8]

 < 0.001

Mitral A-(cm/s)

72.5 [57.8–94.0]

67.3 [57.4–81.0]

66.6 [57.0–87.1]

80.3 [57.7–100.4]

0.461

E/A ratio

1.3 [1.1–1.7]

1.6 [1.2–2.2]

1.6* [1.3–2.1]

1.7* [1.3–2.3]

0.036

A-duration (ms)

120 [109–128]

119 [108–129]

116 [103–129]

107*¶+ [102–116]

0.009

IVRT (ms)

76 [67–98]

68 [51–86]

73 [57–84]

58*¶+ [51–62]

 < 0.001

Average e’ (cm/s)

9.6 [8.0–11.7]

9.6 [7.1–11.2]

9.0 [7.8–10.6]

8.4 [7.3–10.2]

0.325

Average E/e’ ratio

9.8 [8.6–11.4]

10.7 [8.8–14.5]

12.3* [9.7–16.6]

15.5*¶+ [13.1–18.4]

 < 0.001

Pulmonary veins S-wave

(cm/s)

62.6 [48.9–72.9]

48.5 [40.7–60.6]

47.5* [36.8–55.7]

52.3 [40.8–67.9]

0.02

Pulmonary veins D-wave

(cm/s)

50.5 [40.0–65.4]

59.7 [50.3–77.8]

57.4 [48.8–72.4]

71.1*¶+ [57.2–90.2]

0.007

Pulmonary veins S/D

ratio

1.2 [1.0–1.6]

0.8* [0.7–1.0]

0.8* [0.6–1.1]

0.8* [0.6–1.0]

0.002

Pulmonary veins atrial

velocity (cm/s)

28.9 [26.1–33.4]

28.1 [25.3–34]

29.5 [26.2–33.7]

28.8 [25.8–31.9]

0.953

Pulmonary veins atrial

flow duration (Ar) (ms)

126 [113–147]

130 [123–149]

143* [131–160]

150* [136–166]

 < 0.001

TR peak velocity

(cm/s)

220 [182–258]

255* [199–282]

263* [209–317]

292* [247–338]

0.003

Right atrial pressure

(mmHg)

5 [5–5}

5 [5–10]

5 [5–10]

5 [5–10]

0.052

Pulmonary artery systolic

pressure (mmHg)

27 [25–34]

35 [27–49]

39* [29–57]

46* [36–54]

 < 0.001

LV global longitudinal

strain (%)

22.3 [20.9–23.6]

17.7 [16.8–18.5]

21.5 [19.0–23.1]

20.9 [15.7–22.1]

0.324

IVRT/ TE-e’

13.1 [9.4–18.3]

4.3* [1.9–9.3]

2.5* [1.6–4.1]

2.2* [1.6–2.9]

 < 0.001

  1. LAVI – Left atrium maximum volume index, TR-tricuspid regurgitation, IVRT-isovolumic relaxation time, LV-left ventricle, E-mitral inflow early diastolic velocity, A-mitral inflow late diastolic velocity, e’- mitral annulus early diastolic velocity, S-systolic, D-diastolic, TE-e’- time delay between onset of mitral E velocity and onset of mitral annulus e’ velocity.
  2. *, p < 0.05 compared to DF score of 0.
  3. , p < 0.05 compared to DF score of 1.
  4.  + , p < 0.05 compared to DF score of 2.
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