Table 4 Radiobiological comparison of oars among PlanFB, PlanAC and PlanGAT (group A).

From: Dosimetric and radiobiological benefits of patient-specific respiratory motion management for liver tumor stereotactic body radiotherapy

Index

PlanFB

PlanAC

PlanGAT

p-value

Overall

a vs. b

a vs. c

b vs. c

liver EUD (Gy)

44.67 ± 12.83

43.59 ± 12.63

42.29 ± 12.58

< 0.001

< 0.001

< 0.001

< 0.001

liver NTCP (%)

66.01 ± 37.49

62.79 ± 38.14

58.16 ± 38.57

< 0.001

0.231

< 0.001

0.001

left kidney EUD (Gy)

1.91 ± 3.03

1.62 ± 2.47

1.45 ± 2.36

< 0.001

0.030

< 0.001

0.166

right kidney EUD (Gy)

7.32 ± 9.77

6.70 ± 9.60

3.94 ± 6.23

< 0.001

0.906

< 0.001

< 0.001

duodenum EUD (Gy)

14.27 ± 18.60

12.26 ± 14.82

9.70 ± 12.32

< 0.001

0.421

< 0.001

0.055

intestine EUD (Gy)

9.16 ± 13.04

7.11 ± 12.24

4.88 ± 6.66

< 0.001

0.015

< 0.001

0.098

stomach EUD (Gy)

15.90 ± 19.21

14.79 ± 17.42

12.17 ± 14.24

< 0.001

0.421

< 0.001

0.055

spinal cord EUD (Gy)

14.99 ± 8.48

14.15 ± 8.35

14.51 ± 8.74

0.129

0.045

0.243

0.383

  1. a: PlanFB: free breathing treatment plan; b: PlanAC: abdominal compression treatment plan; c: PlanGAT: respiratory gating treatment plan; EUD: equivalent uniform dose (Gy); NTCP: normal tissue complication probability (%).