Table 2 The comparison of disease severity, data at initial admission and clinical outcome in patients with different selenium serum levels.
From: Impact of selenium status and supplementation on outcomes in critically ill patients
Total sample n = 144 | Selenium level < 70 µg/L (n = 40) | Selenium level ≥ 70 µg/L (n = 104) | P value | |
|---|---|---|---|---|
Disease severity | ||||
APACHE II | 21.4 ± 8.5 | 24.7 ± 9.3 | 20.1 ± 7.8 | 0.003 |
SOFA | 7.2 ± 4.1 | 8.6 ± 4.3 | 6.6 ± 3.9 | 0.012 |
TISS | 29.0 ± 7.9 | 31.4 ± 9.4 | 28.1 ± 7.0 | 0.023 |
Glasgow coma scale | 9.5 ± 4.4 | 9.0 ± 4.7 | 9.7 ± 4.2 | 0.307 |
P/F ratio < 300 | 50(34.7%) | 18(45%) | 32(30.8%) | 0.108 |
Mechanical ventilation (%) | 93(64.6%) | 29(72.5%) | 64(61.5%) | 0.218 |
Coronavirus disease 2019 | 23(16.0%) | 5(12.5%) | 18(17.3%) | 0.481 |
14 days re-admission | 20(13.9%) | 2(5%) | 18(17.3%) | 0.063 |
Cause of ICU admission | ||||
Sepsis | 83(57.6%) | 29(72.5%) | 54(51.9%) | 0.025 |
Septic shock | 59(41%) | 22(55%) | 37(35.6%) | 0.034 |
Gastrointestinal bleeding | 11(7.6%) | 1(2.5%) | 10(9.6%) | 0.291 |
Pneumonia | 67(46.5%) | 20(50%) | 47(45.2%) | 0.604 |
Vital signs at ICU admission | ||||
Temperature | 36.3 ± 0.9 | 36.3 ± 0.7 | 36.3 ± 1.0 | 0.903 |
Mean arterial pressure | 88.2 ± 19.4 | 79.9 ± 18.7 | 91.3 ± 18.9 | 0.002 |
Heart rate | 88.3 ± 24.7 | 89.7 ± 25.1 | 87.8 ± 24.7 | 0.679 |
Respiratory rate | 17.8 ± 6.9 | 19.3 ± 7.8 | 17.3 ± 6.4 | 0.117 |
Laboratory data | ||||
25(OH)D | 20.8 ± 9.3 | 16.0 ± 7.5 | 22.6 ± 9.3 | < 0.001 |
Calcium | 7.9 ± 0.9 | 7.6 ± 0.8 | 8.1 ± 0.8 | 0.003 |
Phosphorus | 4.3 ± 11.8 | 3.2 ± 1.5 | 4.7 ± 13.8 | 0.500 |
Sodium | 137.9 ± 13.2 | 138.2 ± 5.6 | 137.8 ± 15.1 | 0.880 |
Potassium | 3.8 ± 1.7 | 3.6 ± 0.6 | 3.9 ± 1.9 | 0.291 |
Blood urea nitrogen | 37.6 ± 26.8 | 42.3 ± 30.3 | 35.9 ± 25.4 | 0.256 |
Creatinine | 2.0 ± 2.4 | 2.3 ± 2.4 | 1.9 ± 2.4 | 0.403 |
Lactate | 2.9 ± 2.8 | 3.6 ± 3.5 | 2.6 ± 2.4 | 0.088 |
CRP | 104.8 ± 93.5 | 162.4 ± 99.2 | 82.1 ± 81.0 | < 0.001 |
PH | 7.41 ± 0.07 | 7.40 ± 0.09 | 7.42 ± 0.06 | 0.320 |
PCO2 | 32.3 ± 8.9 | 31.6 ± 9.4 | 32.5 ± 8.8 | 0.618 |
PaO2 | 112.8 ± 50.1 | 111.0 ± 49.1 | 113.6 ± 50.8 | 0.790 |
P/F ratio | 375.6 ± 205.5 | 311.5 ± 148.8 | 399.5 ± 218.9 | 0.009 |
FiO2 | 37.3 ± 18.2 | 43.4 ± 23.4 | 35.0 ± 15.3 | 0.049 |
White blood cells | 14.3 ± 9.7 | 15.6 ± 13.5 | 13.8 ± 7.7 | 0.452 |
Hemoglobin | 10.7 ± 7.4 | 10.2 ± 2.3 | 11.0 ± 8.6 | 0.608 |
Outcome | ||||
ICU survival | 116(80.6%) | 32(80%) | 84(80.8%) | 0.917 |
ICU length | 10.3 ± 8.1 | 12.5 ± 10.1 | 9.5 ± 7.1 | 0.083 |
Hospital survival | 94(65.3%) | 22 (55%) | 72(69.2%) | 0.108 |
