Table 6 The comparison of disease severity, data at initial admission and clinical outcome in 67 patients received selenium administration with and without ICU survival.
From: Impact of selenium status and supplementation on outcomes in critically ill patients
Total sample n = 67 | ICU survival n = 58 | ICU mortality n = 9 | P value | |
|---|---|---|---|---|
Disease severity | ||||
APACHE II | 22.0 ± 8.6 | 21.3 ± 8.8 | 26.4 ± 6.0 | 0.057 |
SOFA | 7.6 ± 4.0 | 7.1 ± 3.9 | 10.7 ± 3.4 | 0.007 |
TISS | 28.8 ± 7.8 | 28.1 ± 7.9 | 33.6 ± 5.3 | 0.020 |
Glasgow coma scale | 8.9 ± 4.4 | 9.0 ± 4.5 | 7.9 ± 3.6 | 0.492 |
P/F ratio < 300 | 25(37.3%) | 17(29.3%) | 8(88.9%) | 0.001 |
Mechanical ventilation (%) | 45(67.2%) | 37 (63.8%) | 8(88.9%) | 0.252 |
Cause of ICU admission | ||||
Sepsis | 40(59.7%) | 31(53.4%) | 9(100%) | 0.009 |
Septic shock | 29(43.3%) | 20(69%) | 9(100%) | < 0.001 |
Gastrointestinal bleeding | 7(10.4%) | 7(12.1%) | 0(0%) | 0.581 |
Pneumonia | 32 (47.8%) | 27(46.6%) | 5(55.6%) | 0.727 |
Vital signs at ICU admission | ||||
Temperature | 36.3 ± 0.7 | 36.3 ± 0.7 | 36.4 ± 0.5 | 0.879 |
Mean arterial pressure | 87.6 ± 20.0 | 87.5 ± 19.3 | 87.9 ± 25.0 | 0.711 |
Heart rate | 91.1 ± 23.2 | 91.3 ± 22.8 | 90.2 ± 26.8 | 0.909 |
Respiratory rate | 17.0 ± 6.3 | 16.3 ± 5.5 | 21.3 ± 9.5 | 0.102 |
Laboratory data | ||||
25(OH)D | 19.2 ± 8.6 | 19.2 ± 9.0 | 19.3 ± 4.8 | 0.806 |
Blood urea nitrogen | 38.0 ± 25.6 | 37.8 ± 27.2 | 39.1 ± 13.3 | 0.356 |
Creatinine | 1.7 ± 1.6 | 1.8 ± 1.8 | 1.5 ± 0.8 | 0.899 |
Lactate | 2.5 ± 1.6 | 2.5 ± 1.7 | 2.3 ± 0.8 | 0.801 |
Albumin | 2.7 ± 0.5 | 2.8 ± 0.5 | 2.4 ± 0.5 | 0.139 |
CRP | 107.6 ± 100.3 | 108.4 ± 102.6 | 103.2 ± 91.8 | 0.862 |
PH | 7.41 ± 0.07 | 7.42 ± 0.06 | 7.37 ± 0.11 | 0.300 |
PCO2 | 33.3 ± 10.0 | 32.5 ± 7.4 | 38.9 ± 20.5 | 0.149 |
PaO2 | 112.0 ± 56.4 | 111.2 ± 42.8 | 116.6 ± 110.1 | 0.130 |
P/F ratio | 371.9 ± 209.1 | 401.9 ± 204.7 | 198.4 ± 145.6 | 0.001 |
FiO2 | 36.9 ± 17.4 | 33.0 ± 13.0 | 58.3 ± 23.5 | < 0.001 |
White blood cells | 13.6 ± 8.4 | 12.3 ± 7.0 | 22.0 ± 12.5 | 0.024 |
Hemoglobin | 10.1 ± 2.2 | 10.1 ± 2.3 | 10.2 ± 0.9 | 0.526 |