Table 3 Top correlated brain structural changes for each cognitive score.

From: Machine learning-based estimation of the mild cognitive impairment stage using multimodal physical and behavioral measures

 

Positively correlated

Pearson’s r

Spearman’s ρ

p Value for r

p Value for ρ

Negatively correlated

Pearson’s r

Spearman’s ρ

p Value for r

p Value for ρ

SBT-K

rh_occipital(total WMHs)

0.283

0.273

0.293

0.030

GrayVol_lh.rostralanteriorcingulate

 − 0.356

 − 0.319

0.036

0.040

MMSE-KC

GrayVol_lh.caudalanteriorcingulate

0.395

0.381

0.032

0.024

MeanCurv_lh.temporalpole

 − 0.345

 − 0.287

0.036

0.053

Total score of CERAD-K

CurvInd_lh.bankssts

0.293

0.134

0.048

0.381

CurvInd_lh.lingual

 − 0.225

0.04

0.105

0.809

Word List Memory

FoldInd_lh.bankssts

0.320

0.095

0.038

0.563

CurvInd_lh.lingual

 − 0.254

 − 0.05

0.072

0.775

Word List Recall

FoldInd_lh.bankssts

0.320

0.003

0.038

0.983

CurvInd_lh.lingual

 − 0.272

 − 0.08

0.059

0.634

Word List Recognition

FoldInd_lh.bankssts

0.322

0.03

0.038

0.853

CurvInd_lh.lingual

 − 0.261

 − 0.163

0.066

0.277

Constructional Praxis

GrayVol_lh.parsorbitalis

0.400

0.396

0.032

0.024

GausCurv_lh.bankssts

 − 0.347

 − 0.13

0.036

0.400

Constructional Praxis Recall

GrayVol_lh.rostralanteriorcingulate

0.427

0.431

0.032

0.024

MeanCurv_lh.temporalpole

 − 0.354

 − 0.359

0.036

0.028

Verbal Fluency

GrayVol_rh.rostralanteriorcingulate

0.403

0.392

0.032

0.024

GausCurv_rh.inferiortemporal

 − 0.287

 − 0.296

0.051

0.050

Boston Naming Test

GrayVol_lh.rostralanteriorcingulate

0.372

0.349

0.036

0.028

lh_temporal (PV WMHs)

 − 0.268

 − 0.248

0.293

0.059

  1. SBT-K Short blessed test, Korean version; MMSE-KC Mini-mental state examination, Korean version; CERAD-K Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet Korean Version; rh Right hemisphere; WMH White matter hyperintensity; Vol Volume; lh Left hemisphere; CurvInd Curvature index; bankssts banks of the superior temporal sulcus; FoldInd Folding index; MeanCurv Mean curvature; GausCurv Gaussian curvature; PV Periventricular.