Table 3 Top correlated brain structural changes for each cognitive score.
Positively correlated | Pearson’s r | Spearman’s ρ | p Value for r | p Value for ρ | Negatively correlated | Pearson’s r | Spearman’s ρ | p Value for r | p Value for ρ | |
|---|---|---|---|---|---|---|---|---|---|---|
SBT-K | rh_occipital(total WMHs) | 0.283 | 0.273 | 0.293 | 0.030 | GrayVol_lh.rostralanteriorcingulate | − 0.356 | − 0.319 | 0.036 | 0.040 |
MMSE-KC | GrayVol_lh.caudalanteriorcingulate | 0.395 | 0.381 | 0.032 | 0.024 | MeanCurv_lh.temporalpole | − 0.345 | − 0.287 | 0.036 | 0.053 |
Total score of CERAD-K | CurvInd_lh.bankssts | 0.293 | 0.134 | 0.048 | 0.381 | CurvInd_lh.lingual | − 0.225 | 0.04 | 0.105 | 0.809 |
Word List Memory | FoldInd_lh.bankssts | 0.320 | 0.095 | 0.038 | 0.563 | CurvInd_lh.lingual | − 0.254 | − 0.05 | 0.072 | 0.775 |
Word List Recall | FoldInd_lh.bankssts | 0.320 | 0.003 | 0.038 | 0.983 | CurvInd_lh.lingual | − 0.272 | − 0.08 | 0.059 | 0.634 |
Word List Recognition | FoldInd_lh.bankssts | 0.322 | 0.03 | 0.038 | 0.853 | CurvInd_lh.lingual | − 0.261 | − 0.163 | 0.066 | 0.277 |
Constructional Praxis | GrayVol_lh.parsorbitalis | 0.400 | 0.396 | 0.032 | 0.024 | GausCurv_lh.bankssts | − 0.347 | − 0.13 | 0.036 | 0.400 |
Constructional Praxis Recall | GrayVol_lh.rostralanteriorcingulate | 0.427 | 0.431 | 0.032 | 0.024 | MeanCurv_lh.temporalpole | − 0.354 | − 0.359 | 0.036 | 0.028 |
Verbal Fluency | GrayVol_rh.rostralanteriorcingulate | 0.403 | 0.392 | 0.032 | 0.024 | GausCurv_rh.inferiortemporal | − 0.287 | − 0.296 | 0.051 | 0.050 |
Boston Naming Test | GrayVol_lh.rostralanteriorcingulate | 0.372 | 0.349 | 0.036 | 0.028 | lh_temporal (PV WMHs) | − 0.268 | − 0.248 | 0.293 | 0.059 |