Table 3 Mediation analysis of diabetes in the association between UHR and AAC scores, and the prevalence of AAC and SAAC.

From: Diabetes mediates the association between uric acid to high-density lipoprotein cholesterol ratio and abdominal aortic calcification: a cross-sectional study

 

AAC Scores

AAC

SAAC

Estimate

p-value

Estimate

p-value

Estimate

p-value

Total Effect

0.418

0.002

0.058

< 0.0001

0.024

0.006

Averaged Causal Mediation Effects

0.031

0.022

0.003

0.096

0.003

0.002

Average Direct Effect

0.387

0.006

0.055

< 0.0001

0.021

0.016

Prop. Mediated

0.075

0.024

0.043

0.096

0.140

0.008

  1. In the mediation analysis, adjustments were made for sex, age, race, PIR, marital status, education level, BMI, smoked, diabetes, hypertension, serum calcium, serum phosphorus, serum creatinine and 25-hydroxyvitamin D.
  2. PIR, the ratio of income to poverty; BMI, Body Mass Index; AAC, abdominal aortic calcification. SAAC, severe abdominal aortic calcification.