Fig. 3 | Scientific Reports

Fig. 3

From: Gross tumor assessment is not a reliable measure of the efficacy of chemo-preventive agents for breast cancer in preclinical mouse models

Fig. 3

Comparison between gross assessment and histological grading- two different methods of drug efficacy measurement. Analysis limited to animals in drug treatment groups. (A) Analysis of drug efficacy per gland irrespective of the treatment. Response to treatment was significantly greater when tumor assessments were performed by palpation method vs. histologic grading method. (B) Analysis of drug efficacy per mouse. Mice were considered to be non-responders if at least one gland was palpable and/or carried histologic grade 4 or 5 lesion.

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