Table 3 Comparative table summarizes the healing dynamics based on the structural properties of both SC implants and highlights their impact on FBR and the healing process.
Feature | Ulva sp. | Cl sp. |
|---|---|---|
Scaffold type | Porous, interconnected scaffold | Fibrous, dense scaffold |
Healing dynamics | Interspersed distributed healing | Concentric stratification: radial healing |
Healing progression | Compartmentalized, simultaneous expansion, across entire scaffold | Center-periphery, outward expansion, layer-by-layer |
Inflammation | Evenly distributed among cavity-collections, gradually reduced | Initially concentrated in the necrotic center, resolves outward |
Fibrosis & collagen deposition | Forms interspersed connective tissue septa, with mature collagen | Forms a dense, organized fibrosis core, collagen surrounding individual fibers |
Neovascularization | Interspersed throughout the scaffold | Peripheral at early stages, shifts toward center |
Neovascularization morphologies | Luminal morphology within tissue septa collections | Branching-like structures within the dense fibrous |
FBR resolution | MCs and FBGCs slow and gradual reduce, however persist | Peripheral FBGCs persist longer |
Healing efficiency | Supports sustained, gradual integration | Favoring rapid, organized remodeling |
Ideal for | Randomized healing applications, wound healing | Fibrotic tissue engineering, guided tissue formation |
