Fig. 5

FAM83D regulated by HMMR and influence the Wnt signaling pathway. (A) KEGG and GO enrichment analysis of different expression genes. (B) Interaction between HMMR and β-catenin by Co-IP analyses in SUNE1 cells. (C) Protein binding to HMMR was detected by CO-IP/MS analysis. (D) Interaction between HMMR and FAM83D by Co-IP analyses in SUNE1 cells. (E) SUNE1-shHMMR cells transfected with pcDNA3-FAM83D was subjected to western blot for indicated proteins. (F) CNE2-pcDNA3-HMMR cells transfected with shFAM83D was subjected to western blot for indicated proteins.