Fig. 2
From: A novel D-peptide modulates DCLK1 gelsolin interactions, reducing PDAC tumor growth
Anti-Tumor Effects of DCLK1 D-peptides on Pancreatic Cancer Cells (A-B) Colony Formation Assays: Boxplots show colony counts after treatment in (A) AsPC-1 and (B) Capan-1 pancreatic cancer cells. (C,D) PDAC Spheroid Self-Renewal: Boxplots display spheroid counts following treatment in (C) AsPC-1 and (D) Capan-1 cells. (E,F) In Vivo Efficacy of D-peptide 1: AsPC-1-derived xenografts were treated with D-peptide 1 or control peptide (D-peptide 3) every three days for six doses. (E) Representative tumor images after 36 days of treatment. (F) D-peptide 1 significantly reduced tumor size compared to control (Control n = 8, D-peptide 1 n = 9; *p < 0.01).
