Fig. 2 | Scientific Reports

Fig. 2

From: An integrated structural and immunoinformatic approach to design a multi-epitope based vaccine against the foot-and-mouth disease virus

Fig. 2

Illustration of the final multi-epitope-based vaccine (MEBV) construct. (A) Schematic representation of the arrangements of the adjuvant; PADRE sequence; B-cell, cytotoxic T-lymphocyte (CTL), and helper T-lymphocyte (HTL) epitopes; 6-His tag; and linkers used to construct the MEBV. (B) Complete sequence of the MEBV. (C) Three-dimensional structure of the final MEBV modeled using AlphaFold. The B-cell, CTL, and HTL epitopes are illustrated in light pink, pale green, and light blue, respectively. The adjuvant and PADRE sequences in the N-terminal and 6-His tag in the C-terminal are illustrated in light orange.

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