Fig. 4 | Scientific Reports

Fig. 4

From: Uncovering the anti-cervical cancer mechanism of Ziyuglycoside I via integrated network pharmacology molecular docking and experimental validation

Fig. 4

Inhibition of cervical cancer cell migration by Ziyuglycoside I (Ziyu I): (A) Scratch assay to evaluate the effect of Ziyu I treatment on the migration ability of HeLa and SiHa cells, and photographs were taken at 0 h, 12 h, 24 h–0 h, 24 h, 48 h to record the area of cell migration (100×). (B) Transwell assay: Transwell chambers were used to determine the number of migrating cells in HeLa and SiHa cells after Ziyu I treatment (100×). (C) Western blot analysis of E-cadherin and N-cadherin protein expression levels in HeLa and SiHa cells treated with Ziyu I for 24 h and 48 h.

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