Table 1 Baseline characteristics of patients before and after propensity score matching.
From: Blastocyst quality and congenital malformation risk in singleton births after frozen embryo transfer
Before propensity score matching | After propensity score matching | |||||
|---|---|---|---|---|---|---|
GQE(N = 3023) | PQE(N = 963) | P value | GQE(N = 1162) | PQE(N = 581) | P value | |
Maternal age (years) | < 0.001 | 0.4326 | ||||
˂ 30 | 1301 (43.04%) | 321 (33.33%) | 400 (34.43%) | 215 (37.01%) | ||
30–35 | 1294 (42.81%) | 416 (43.20%) | 535 (46.04%) | 249 (42.86%) | ||
≥ 35 | 428 (14.16%) | 226 (23.47%) | 227 (19.54%) | 117 (20.14%) | ||
Maternal BMI (kg/m2) | 0.721 | 0.5495 | ||||
˂ 18.5 | 170 (5.63%) | 47 (4.89%) | 49 (4.22%) | 30 (5.16%) | ||
18.5 | 2025 (67.03%) | 639 (66.42%) | 802 (69.02%) | 388 (66.78%) | ||
25–30 | 700 (23.17%) | 232 (24.12%) | 253 (21.77%) | 138 (23.75%) | ||
≥ 30 | 126 (4.17%) | 44 (4.57%) | 58 (4.99%) | 25 (4.30%) | ||
Paternal age (years) | < 0.001 | 0.9133 | ||||
˂ 30 | 1123 (37.16%) | 251 (26.06%) | 356 (30.64%) | 176 (30.29%) | ||
30–35 | 1310 (43.35%) | 442 (45.90%) | 512 (44.06%) | 262 (45.09%) | ||
≥ 35 | 589 (19.49%) | 270 (28.04%) | 294 (25.30%) | 143 (24.61%) | ||
Paternal BMI (kg/m2) | 0.954 | 0.4960 | ||||
˂ 18.5 | 68 (2.38%) | 20 (2.21%) | 23 (1.98%) | 12 (2.07%) | ||
18.5 | 1375 (48.03%) | 443 (48.90%) | 555 (47.76%) | 263 (45.27%) | ||
25–30 | 1149 (40.13%) | 361 (39.85%) | 439 (37.78%) | 235 (40.45%) | ||
≥ 30 | 271 (9.47%) | 82 (9.05%) | 116 (9.98%) | 48 (8.26%) | ||
Basal FSH (IU/L) | 6.25 ± 1.50 | 6.54 ± 1.64 | < 0.001 | 6.40 ± 1.53 | 6.36 ± 1.51 | 0.6160 |
Basal AMH (ng/mL) | 4.38[2.80, 6.56] | 3.29[2.03, 5.29] | < 0.001 | 4.05[2.44,5.87] | 3.69[2.24,5.87] | 0.1920 |
Primary infertility | 1326 (43.86%) | 313 (32.50%) | < 0.001 | 402 (34.60%) | 201 (34.60%) | 1.0000 |
Infertility duration | < 0.001 | 0.9553 | ||||
≤ 2 years | 1149 (38.31%) | 269 (28.05%) | 337 (29.00%) | 167 (28.74%) | ||
≥ 3 years | 1850 (61.69%) | 690 (71.95%) | 825 (71.00%) | 414 (71.26%) | ||
Primiparous (%) | 2067 (68.38%) | 524 (54.41%) | < 0.001 | 648 (55.77%) | 331 (56.97%) | 0.6696 |
Causes of infertility | 0.45 | 0.1950 | ||||
Tubal factor | 1420 (46.97%) | 445 (46.21%) | 566 (48.71%) | 272 (46.82%) | ||
PCOS | 313 (10.35%) | 87 (9.03%) | 102 (8.78%) | 65 (11.19%) | ||
Endometriosis | 59 (1.95%) | 27 (2.80%) | 14 (1.21%) | 12 (2.07%) | ||
Male factor | 300 (9.92%) | 92 (9.55%) | 135 (11.62%) | 52 (8.95%) | ||
Mixed factors | 73 (2.41%) | 22 (2.28%) | 30 (2.58%) | 15 (2.58%) | ||
Others | 858 (28.38%) | 290 (30.11%) | 315 (27.11%) | 165 (28.40%) | ||
FET cycle number | 0.018 | 0.2967 | ||||
1 | 2645 (87.50%) | 814 (84.53%) | 1022 (87.95%) | 500 (86.06%) | ||
≥ 2 | 378 (12.50%) | 149 (15.47%) | 140 (12.05%) | 81 (13.94%) | ||
Fertilization method | 0.011 | 0.5051 | ||||
IVF | 2230 (73.77%) | 670 (69.57%) | 853 (73.41%) | 417 (71.77%) | ||
ICSI | 793 (26.23%) | 293 (30.43%) | 309 (26.59%) | 164 (28.23%) | ||
FET endometrial preparation | < 0.001 | 0.7682 | ||||
Natural cycle | 972 (32.15%) | 408 (42.37%) | 454 (39.07%) | 232 (39.93%) | ||
Hormone therapy cycle | 2051 (67.85%) | 555 (57.63%) | 708 (60.93%) | 349 (60.07%) | ||
Development stage at transfer | < 0.001 | 0.2514 | ||||
Day 5 | 2655 (87.83%) | 597 (61.99%) | 1063 (91.48%) | 521 (89.67%) | ||
Day 6 | 368 (12.17%) | 366 (38.01%) | 99 (8.52%) | 60 (10.33%) | ||
