Table 3 Multivariate logistic regression analysis of neonatal and obstetric outcomes between good-quality and poor-quality blastocyst groups.

From: Blastocyst quality and congenital malformation risk in singleton births after frozen embryo transfer

 

Non-adjusted

Adjusted

OR (95% CI)

P value

OR (95% CI)

P value

Congenital malformations

1.20 (0.58, 2.48)

0.6143

1.14 (0.54, 2.41)

0.7310

Neonatal gender

0.91 (0.75, 1.12)

0.3704

0.93 (0.75, 1.14)

0.4720

Preterm birth

0.83 (0.60, 1.15)

0.2597

0.80 (0.57, 1.12)

0.1976

VLBW (very low birth weight)

1.43 (0.45, 4.53)

0.5410

1.52 (0.47, 4.90)

0.4832

LBW (low birth weight)

1.29 (0.76, 2.20)

0.3502

1.26 (0.72, 2.19)

0.4172

HBW (high birth weight)

2.02 (0.83, 4.87)

0.1189

2.49 (0.94, 6.65)

0.0677

VSGA (very small for gestational age

0.75 (0.20, 2.83)

0.6699

0.77 (0.20, 2.98)

0.7053

SGA (small for gestational age)

1.13 (0.63, 2.03)

0.6850

1.10 (0.61, 1.99)

0.7461

LGA (large for gestational age)

1.16 (0.94, 1.43)

0.1785

1.17 (0.94, 1.45)

0.1691

VLGA (very large for gestational age)

1.14 (0.87, 1.51)

0.3412

1.14 (0.85, 1.52)

0.3832

Mode of delivery

0.91 (0.72, 1.16)

0.4446

0.87 (0.68, 1.12)

0.2806

Obstetric complications

0.94 (0.69, 1.27)

0.6803

0.89 (0.64, 1.22)

0.4629

Gestational hypertension

0.63 (0.37, 1.08)

0.0956

0.54 (0.30, 1.04)

0.0519

Gestational diabetes

1.57 (0.94, 2.62)

0.0847

1.46 (0.85, 2.50)

0.1660

Amniotic fluid abnormalities

0.66 (0.18, 2.47)

0.5417

0.77 (0.20, 2.94)

0.6980

Premature rupture of membranes

0.74 (0.41, 1.36)

0.3342

0.77 (0.42, 1.41)

0.3910

Placenta previa

3.02 (0.85, 10.75)

0.0877

2.94 (0.82, 10.61)

0.0990

Cervical insufficiency

0.36 (0.08, 1.64)

0.1865

0.42 (0.09, 1.99)

0.2764

Stillbirth

1.50 (0.34, 6.74)

0.5948

1.73 (0.37, 8.01)

0.4824

  1. Values are reported as β (95% CI), P value, or OR (95% CI), P value. P values were calculated using the chi-square test. Multivariate logistic regression analysis was performed to assess the association between embryo quality and obstetric outcomes. The model was adjusted for fertilization method (IVF, ICSI), treatment regimen (natural cycle, hormone replacement cycle), embryo development stage (D5, D6), primiparous (yes, no), maternal age group (< 30, 30–35, ≥ 35), maternal BMI group (< 18.5, 18.5–25, 25–30, ≥ 30), paternal age group (< 30, 30–35, ≥ 35), and paternal BMI group (< 18.5, 18.5–25, 25–30, ≥ 30). Results are expressed as adjusted odds ratios (OR) with corresponding 95% confidence intervals (CI).
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