Table 1 Baseline demographics and laboratory tests.
Total (N = 70) | D&E (N = 35) | Control (N = 35) | P-value | |
|---|---|---|---|---|
Demographics | ||||
Age (y) | 53.7 ± 14 | 55.1 ± 13 | 52.4 ± 15 | 0.444 |
Male sex (n, %) | 45 (64.3%) | 21 (60.0%) | 24 (68.6%) | 0.618 |
Height (cm) | 165.9 ± 8 | 165.2 ± 8 | 166.7 ± 8 | 0.450 |
Weight (kg) | 73.7 ± 14 | 72.1 ± 13 | 75.4 ± 15 | 0.346 |
BMI (kg/m2) | 26.6 ± 3 | 26.3 ± 3 | 26.9 ± 3 | 0.496 |
DM (n, %) | 9 (12.9%) | 7 (20.0%) | 2 (5.7%) | 0.153 |
Dyslipidemia (n, %) | 40 (57.1%) | 19 (54.3%) | 21 (60.0%) | 0.809 |
Current smoker (n, %) | 13 (18.6%) | 6 (17.1%) | 7 (20.0%) | 1.000 |
Alcohol drinking (n, %) | 38 (54.3%) | 17 (48.6%) | 21 (60.0%) | 0.472 |
Medications | ||||
Aspirin (n, %) | 6 (8.6%) | 2 (5.7%) | 4 (11.4%) | 0.669 |
Clopidogrel (n, %) | 11 (15.7%) | 4 (11.4%) | 7 (20.0%) | 0.511 |
Statins (n, %) | 27 (38.6%) | 12 (34.3%) | 15 (42.9%) | 0.623 |
Fenofibrate (n, %) | 2 (2.9%) | 2 (5.7%) | 0 (0.0%) | 0.473 |
Ezetimibe (n, %) | 16 (22.9%) | 7 (20.0%) | 9 (25.7%) | 0.776 |
DM medications (n, %) | 6 (8.6%) | 5 (14.3%) | 1 (2.9%) | 0.200 |
BP measurements | ||||
24-hour SBP (mmHg) | 133.1 ± 8 | 134.4 ± 9 | 131.6 ± 7 | 0.162 |
24-hour DBP (mmHg) | 84.7 ± 9 | 85.9 ± 10 | 83.4 ± 7 | 0.258 |
24-hour daytime SBP (mmHg) | 135.4 ± 8 | 136.8 ± 9 | 133.9 ± 7 | 0.17 |
24-hour daytime DBP (mmHg) | 86.7 ± 10 | 87.9 ± 11 | 85.3 ± 8 | 0.297 |
24-hour nighttime SBP (mmHg) | 126.1 ± 10 | 127.1 ± 12 | 125.0 ± 9 | 0.421 |
24-hour nighttime DBP (mmHg) | 78.8 ± 9 | 79.7 ± 10 | 77.9 ± 8 | 0.440 |
Office SBP (mmHg) | 140.1 ± 7 | 141.4 ± 7 | 138.9 ± 7 | 0.155 |
Office DBP (mmHg) | 86.0 ± 8 | 87.4 ± 9 | 84.7 ± 7 | 0.169 |
Central SBP (mmHg) | 148.1 ± 17 | 151.1 ± 17 | 144.8 ± 18 | 0.159 |
Augmentation index | 81.0 ± 17 | 83.6 ± 19 | 78.2 ± 14 | 0.214 |
PWV (cm/s) | 1566.2 ± 250 | 1609.8 ± 247 | 1516.9 ± 248 | 0.139 |
Laboratory tests | ||||
HbA1c (% of total Hb) | 5.7 ± 0.6 | 5.8 ± 0.6 | 5.6 ± 0.5 | 0.328 |
Fasting glucose (mg/dL) | 107.4 ± 26 | 112.5 ± 34 | 102.6 ± 13 | 0.140 |
BUN (mg/dL) | 14.6 ± 4 | 15.2 ± 3 | 13.9 ± 4 | 0.190 |
Creatinine (mg/dL) | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.440 |
WBC (x109/L) | 6.3 ± 1.6 | 6.3 ± 1.7 | 6.2 ± 1.6 | 0.734 |
hsCRP (mg/L) | 0.9 ± 1.1 | 0.7 ± 0.7 | 1.1 ± 1.4 | 0.241 |
ESR (mm/h) | 9.3 ± 8.2 | 8.9 ± 7.8 | 9.8 ± 8.7 | 0.666 |
Renin (ng/ml/h) | 1.9 ± 1.8 | 1.4 ± 1.3 | 2.3 ± 2.2 | 0.069 |
IL-6 (pg/mL) | 3.8 ± 2.3 | 3.3 ± 2.0 | 4.3 ± 2.5 | 0.102 |
IL-18 (pg/mL) | 226.1 ± 80 | 228.0 ± 71 | 224.0 ± 90 | 0.852 |
VCAM-1 (ng/mL) | 798.3 ± 203 | 815.3 ± 200 | 780.7 ± 207 | 0.54 |
ICAM-1 (ng/mL) | 220.3 ± 69 | 212.8 ± 79 | 227.8 ± 58 | 0.424 |
TNF-α (pg/mL) | 1.0 ± 0.3 | 1.0 ± 0.3 | 0.9 ± 0.3 | 0.429 |
PAI-1 (ng/mL) | 52.2 ± 34 | 47.6 ± 30 | 51.7 ± 34 | 0.639 |
