Table 1 Experimental design, animal model construction.
Group | Mode of modeling and administration |
|---|---|
Control group | Normal rats were injected with an equal volume of normal saline intraperitoneally |
POI group | CTX was injected intraperitoneally at a dose of 200 mg/kg initially, and then continuously at a dose of 8 mg/kg for 15 days |
QR group | Starting from the modeling day, 100 mg/kg/d QR was orally administered for 30 days |
QR + POI group | Starting from the modeling day, 100 mg/kg/d QR was orally administered for 30 days |
EV + POI group | 20 mg/kg/d estradiol valerate was given by gavage for 30 days from the day of modeling |
