Table 1 Baseline demographic and clinical characteristics of EOCRC-LM patients.

From: Prognostic model for early-onset colorectal cancer with liver metastasis after primary tumor resection and chemotherapy

Variables

Total (n = 1049)

Training (n = 734)

Validation (n = 315)

P value

Age

0.349

  ≤ 29

44 ( 4.2%)

28 (3.8%)

16 (5.1%)

 

 30–49

1005 (95.8%)

706 (96.2%)

299 (94.9%)

 

Sex

0.79

 Female

473 (45.1%)

329 (44.8%)

144 (45.7%)

 

 Male

576 (54.9%)

405 (55.2%)

171 (54.3%)

 

Race

0.311

 White

767 (73.1%)

541 (73.7%)

226 (71.7%)

 

 Black

164 (15.6%)

107 (14.6%)

57 (18.1%)

 

 Other

118 (11.2%)

86 (11.7%)

32 (10.2%)

 

Marital status

0.558

 Married

572 (54.5%)

401 (54.6%)

171 (54.3%)

 

 UnMarried/Single

352 (33.6%)

241 (32.8%)

111 (35.2%)

 

 Divorced/Separated/Widowed

125 (11.9%)

92 (12.5%)

33 (10.5%)

 

Site

0.104

 Left-side

542 (51.7%)

372 (50.7%)

170 (54%)

 

 Right-side

313 (29.8%)

214 (29.2%)

99 (31.4%)

 

 Rectum

194 (18.5%)

148 (20.2%)

46 (14.6%)

 

Tumor size

0.488

  ≤ 5 cm

530 (50.5%)

376 (51.2%)

154 (48.9%)

 

  > 5 cm

519 (49.5%)

358 (48.8%)

161 (51.1%)

 

Histologic

0.882

 Adenocarcinoma

948 (90.4%)

665 (90.6%)

283 (89.8%)

 

 Mucinous adenocarcinoma

64 ( 6.1%)

43 (5.9%)

21 (6.7%)

 

 Other

37 ( 3.5%)

26 (3.5%)

11 (3.5%)

 

T

0.834

 T1

35 ( 3.3%)

24 (3.3%)

11 (3.5%)

 

 T2

38 ( 3.6%)

29 (4%)

9 (2.9%)

 

 T3

622 (59.3%)

436 (59.4%)

186 (59%)

 

 T4

354 (33.7%)

245 (33.4%)

109 (34.6%)

 

N

0.637

 N0

167 (15.9%)

118 (16.1%)

49 (15.6%)

 

 N1

397 (37.8%)

271 (36.9%)

126 (40%)

 

 N2

485 (46.2%)

345 (47%)

140 (44.4%)

 

Radiotherapy

0.244

 None/Unknown

906 (86.4%)

628 (85.6%)

278 (88.3%)

 

 Yes

143 (13.6%)

106 (14.4%)

37 (11.7%)

 

CEA

0.582

 Negative

158 (15.1%)

115 (15.7%)

43 (13.7%)

 

 Positive

622 (59.3%)

436 (59.4%)

186 (59%)

 

 Unknown

269 (25.6%)

183 (24.9%)

86 (27.3%)

 

Regional nodes examined

0.461

  ≤ 17

561 (53.5%)

398 (54.2%)

163 (51.7%)

 

  > 17

488 (46.5%)

336 (45.8%)

152 (48.3%)

 

Bone metastasis

0.421

 No

1019 (97.1%)

715 (97.4%)

304 (96.5%)

 

 Yes

30 ( 2.9%)

19 (2.6%)

11 (3.5%)

 

Lung metastasis

0.431

 No

885 (84.4%)

615 (83.8%)

270 (85.7%)

 

 Yes

164 (15.6%)

119 (16.2%)

45 (14.3%)