Fig. 1 | Scientific Reports

Fig. 1

From: IL27RA promotes the proliferation and metastasis of hepatocellular carcinoma cells by regulating TGFβR1

Fig. 1

Expression of IL27RA in hepatocellular carcinoma and its prognostic significance. (A–C) TCGA database analysis revealed that the transcription level of IL27RA was greater in liver cancer tissues than in paracarcinoma tissues and that high expression of IL27RA was associated with poorer overall survival. (D) The expression levels of IL27RA in HCC tissues (T) and paired noncancerous tissues (N) were detected by Western blotting. (E) The expression levels of IL27RA were analysed via Western blotting in HepaRG cells and other liver cancer cell lines. (F) Immunohistochemical staining of IL27RA in human HCC tissues was performed; representative images are presented. (G) The expression levels of IL27RA in HCC and nontumor tissue were statistically analysed, the results were statistically significant (p < 0.0001). (H) Kaplan–Meier analysis demonstrated that patients with high expression of IL27RA had shorter overall survival. The data are presented as the mean ± SDs.

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